PMID- 23280026
OWN - NLM
STAT- MEDLINE
DCOM- 20130612
LR  - 20181202
IS  - 1128-3602 (Print)
IS  - 1128-3602 (Linking)
VI  - 16
IP  - 15
DP  - 2012 Dec
TI  - Latest advancements in the pharmacological treatment of binge eating disorder.
PG  - 2102-7
AB  - BACKGROUND: Binge-eating disorder (BED) is a relatively new disorder 
      characterized by binge eating without purging. AIM: The purpose of this article 
      is to review the potential use of the recently proposed compounds for the 
      treatment of BED. MATERIALS AND METHODS: A medline of published articles from 
      1980 to December 2012 was carried out using the following keywords: BED and 
      treatment, topiramate, zonisamide, ghrelin. RESULTS: The pharmacological 
      treatment of BED is still heterogenous and poorly established, mainly for the 
      lack of controlled studies in large samples of patients. CONCLUSIONS: The data on 
      serotonin and norepinephrine reuptake inhibitors and on novel anticonvulsants 
      seem quite promising in terms of efficacy and tolerability. In addition, the 
      preliminary findings on the possibility of modulating appetite through the 
      interference with the ghrelin system suggest new and intriguing ways of 
      intervention in BED.
FAU - Marazziti, D
AU  - Marazziti D
AD  - Department of Psychiatry, University of Pisa, Italy. dmarazzi@psico.med.unipi.it
FAU - Corsi, M
AU  - Corsi M
FAU - Baroni, S
AU  - Baroni S
FAU - Consoli, G
AU  - Consoli G
FAU - Catena-Dell'Osso, M
AU  - Catena-Dell'Osso M
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Italy
TA  - Eur Rev Med Pharmacol Sci
JT  - European review for medical and pharmacological sciences
JID - 9717360
RN  - 0 (Ghrelin)
RN  - 0 (Isoxazoles)
RN  - 0H73WJJ391 (Topiramate)
RN  - 30237-26-4 (Fructose)
RN  - 459384H98V (Zonisamide)
SB  - IM
MH  - Binge-Eating Disorder/blood/*drug therapy
MH  - Female
MH  - Fructose/analogs & derivatives/therapeutic use
MH  - Ghrelin/blood/genetics
MH  - Humans
MH  - Isoxazoles/therapeutic use
MH  - Topiramate
MH  - Zonisamide
EDAT- 2013/01/03 06:00
MHDA- 2013/06/13 06:00
CRDT- 2013/01/03 06:00
PHST- 2013/01/03 06:00 [entrez]
PHST- 2013/01/03 06:00 [pubmed]
PHST- 2013/06/13 06:00 [medline]
PST - ppublish
SO  - Eur Rev Med Pharmacol Sci. 2012 Dec;16(15):2102-7.