PMID- 23283060 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20130305 LR - 20230404 IS - 1939-4551 (Print) IS - 1939-4551 (Electronic) IS - 1939-4551 (Linking) VI - 2 IP - 7 DP - 2009 Jul TI - The study of egg allergy in children with atopic dermatitis. PG - 123-7 LID - 10.1097/WOX.0b013e3181abe7cb [doi] AB - CONTEXT: : Food allergy plays a significant pathogenic role among children with atopic dermatitis (AD). OBJECTIVE: : The aims of this study were to evaluate allergy to egg in these children and determine the egg specific immunoglobulin E (IgE) cutoff point. DESIGN AND SETTING: : It was a cross-sectional study that took place at Immunology, Asthma and Allergy Research Institute from 2005 to 2007. METHODS: : Children younger than 14 years old with AD entered the study. Careful medical histories were taken and skin prick and Immuno-CAP tests with the most commonly offending foods (cow's milk, egg, wheat, peanut, and soy) were performed. Children with a clear, positive history of food allergy and a positive IgE-mediated test or those with positive responses to both IgE-mediated tests were determined to have food allergies. The egg-specific IgE level cutoff point was determined. RESULTS: : A hundred patients entered the study (from 2 months to 12 years old). They were divided into 3 age groups: first <2 years, second from 2 to <6 years, and third from 6 to 14 years. The most common food allergens were egg (39.22%) in the first, cow's milk (35.13%) and egg (32.43%) in the second, and peanut (25%) and egg (16.67%) in the third group. The egg-specific IgE cutoff point value was 0.62 kUA/L (kilounits of allergen-specific IgE per liter). The positive predictive value was 95%. CONCLUSION: : Prevalence of egg allergy is highly significant in patients with AD.To use egg-specific IgE level cutoff point, the patient population under study must be considered. FAU - Salehi, Tahmineh AU - Salehi T AD - From the 1Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran; 2Department of Immunology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran. FAU - Pourpak, Zahra AU - Pourpak Z FAU - Karkon, Shahnaz AU - Karkon S FAU - Shoormasti, Raheleh Shokouhi AU - Shoormasti RS FAU - Sabzevari, Samineh Kamali AU - Sabzevari SK FAU - Movahedi, Masoud AU - Movahedi M FAU - Gharagozlou, Mohammad AU - Gharagozlou M FAU - Moin, Mostafa AU - Moin M LA - eng PT - Journal Article PL - United States TA - World Allergy Organ J JT - The World Allergy Organization journal JID - 101481283 PMC - PMC3650957 EDAT- 2009/07/01 00:00 MHDA- 2009/07/01 00:01 PMCR- 2009/07/01 CRDT- 2013/01/04 06:00 PHST- 2013/01/04 06:00 [entrez] PHST- 2009/07/01 00:00 [pubmed] PHST- 2009/07/01 00:01 [medline] PHST- 2009/07/01 00:00 [pmc-release] AID - S1939-4551(19)30540-X [pii] AID - 1939-4551-2-7-123 [pii] AID - 10.1097/WOX.0b013e3181abe7cb [doi] PST - ppublish SO - World Allergy Organ J. 2009 Jul;2(7):123-7. doi: 10.1097/WOX.0b013e3181abe7cb.