PMID- 23283386
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20130104
LR  - 20230404
IS  - 1939-4551 (Print)
IS  - 1939-4551 (Electronic)
IS  - 1939-4551 (Linking)
VI  - 1
IP  - 3
DP  - 2008 Mar
TI  - Immunoglobulin e-mediated allergy plays a role in atopic eczema as shown in the 
      atopy patch test.
PG  - 51-6
LID - 10.1097/WOX.0b013e3181661472 [doi]
AB  - Although the pathophysiology of immunoglobulin E (IgE)-mediated allergic 
      rhinoconjunctivitis and bronchial asthma is rather well established, the role of 
      allergy in atopic eczema (AE) is still controversial. By a technique called atopy 
      patch test, aeroallergens like house dust mite, animal dander, or pollen were 
      proven as relevant trigger factors in a subgroup of patients with AE. The atopy 
      patch test is an epicutaneous patch test with such allergens known to elicit 
      IgE-mediated reactions, and used for the evaluation of eczematous skin reactions. 
      In a series of single-center and multicenter studies, a method was developed, 
      standardized, and compared with other diagnostic techniques (radioallergosorbent 
      test, skin prick test) in AE patients. With regard to clinical history, the most 
      specific results were obtained with the atopy patch test (allergen-dependent, 
      69%-92%), whereas sensitivity was higher for skin prick test (range, 69%-82%) and 
      specific IgE (range, 65%-94%). The characterization of a patient subgroup with 
      relevant IgE-mediated allergy may lead to more efficient avoidance and eventually 
      even specific immunotherapy strategies in the management of AE.
FAU - Darsow, Ulf
AU  - Darsow U
AD  - From the Department of Dermatology and Allergy Biederstein, Division of 
      Environmental Dermatology and Allergy Helmholtz Center/TUM, Technische 
      Universitat Munchen, Munich, Germany.
FAU - Ring, Johannes
AU  - Ring J
LA  - eng
PT  - Journal Article
PL  - United States
TA  - World Allergy Organ J
JT  - The World Allergy Organization journal
JID - 101481283
PMC - PMC3651189
EDAT- 2008/03/01 00:00
MHDA- 2008/03/01 00:01
PMCR- 2008/03/01
CRDT- 2013/01/04 06:00
PHST- 2013/01/04 06:00 [entrez]
PHST- 2008/03/01 00:00 [pubmed]
PHST- 2008/03/01 00:01 [medline]
PHST- 2008/03/01 00:00 [pmc-release]
AID - S1939-4551(19)30572-1 [pii]
AID - 1939-4551-1-3-51 [pii]
AID - 10.1097/WOX.0b013e3181661472 [doi]
PST - ppublish
SO  - World Allergy Organ J. 2008 Mar;1(3):51-6. doi: 10.1097/WOX.0b013e3181661472.