PMID- 23284020
OWN - NLM
STAT- MEDLINE
DCOM- 20130729
LR  - 20211021
IS  - 1098-660X (Electronic)
IS  - 0095-1137 (Print)
IS  - 0095-1137 (Linking)
VI  - 51
IP  - 3
DP  - 2013 Mar
TI  - Association of neurotropic viruses in HIV-infected individuals who died of 
      secondary complications of tuberculosis, cryptococcosis, or toxoplasmosis in 
      South India.
PG  - 1022-5
LID - 10.1128/JCM.03321-12 [doi]
AB  - The frequencies of 10 opportunistic DNA viruses were determined by multiplex 
      real-time PCR in paired cerebrospinal fluid (CSF) and brain tissue of 
      HIV-infected individuals. In the CSF, viruses were detectable in 45/55 cases: JC 
      virus (JCV) in 62%, Epstein-Barr virus (EBV) in 44%, cytomegalovirus (CMV) in 
      25%, varicella-zoster virus (VZV) in 3.6%, herpes simplex virus 1 (HSV-1) in 
      1.8%, and human herpesvirus 6 (HHV-6) in 1.8% of cases. A single virus was 
      detectable in 20 cases, 19 cases had coinfection with two viruses, and 6 cases 
      were positive for three viruses. JCV was detectable in the CSF of 62% of cases 
      and in 42% of brain tissues, with higher loads in progressive multifocal 
      leukoencephalopathy (PML) (P < 0.05).
FAU - Kannangai, Rajesh
AU  - Kannangai R
AD  - Department of Clinical Virology, Christian Medical College, Vellore, India. 
      kannangair@cmcvellore.ac.in
FAU - Sachithanandham, Jaiprasath
AU  - Sachithanandham J
FAU - Mahadevan, Anita
AU  - Mahadevan A
FAU - Abraham, Asha Mary
AU  - Abraham AM
FAU - Sridharan, Gopalan
AU  - Sridharan G
FAU - Desai, Anita
AU  - Desai A
FAU - Ravi, Vasanthapuram
AU  - Ravi V
FAU - Shankar, Susarla Krishna
AU  - Shankar SK
LA  - eng
PT  - Journal Article
DEP - 20130102
PL  - United States
TA  - J Clin Microbiol
JT  - Journal of clinical microbiology
JID - 7505564
SB  - IM
MH  - AIDS-Related Opportunistic Infections/*mortality/virology
MH  - Brain/virology
MH  - Cerebrospinal Fluid/virology
MH  - Cryptococcosis/complications/*mortality
MH  - DNA Virus Infections/*epidemiology/virology
MH  - DNA Viruses/classification/genetics/*isolation & purification
MH  - HIV Infections/*complications
MH  - Humans
MH  - India/epidemiology
MH  - Multiplex Polymerase Chain Reaction
MH  - Prevalence
MH  - Toxoplasmosis/complications/*mortality
MH  - Tuberculosis/complications/*mortality
PMC - PMC3592081
EDAT- 2013/01/04 06:00
MHDA- 2013/07/31 06:00
PMCR- 2013/09/01
CRDT- 2013/01/04 06:00
PHST- 2013/01/04 06:00 [entrez]
PHST- 2013/01/04 06:00 [pubmed]
PHST- 2013/07/31 06:00 [medline]
PHST- 2013/09/01 00:00 [pmc-release]
AID - JCM.03321-12 [pii]
AID - 03321-12 [pii]
AID - 10.1128/JCM.03321-12 [doi]
PST - ppublish
SO  - J Clin Microbiol. 2013 Mar;51(3):1022-5. doi: 10.1128/JCM.03321-12. Epub 2013 Jan 
      2.