PMID- 23285453
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20130104
LR  - 20211021
IS  - 2249-782X (Print)
IS  - 0973-709X (Electronic)
IS  - 0973-709X (Linking)
VI  - 6
IP  - 9
DP  - 2012 Nov
TI  - A Patient with Multiple Immune Reconstitution Inflammatory Syndrome (IRIS) 
      Following Initiation of Antiretroviral Therapy.
PG  - 1547-9
LID - 10.7860/JCDR/2012/4547.2556 [doi]
AB  - The Immune Reconstitution Inflammatory Syndrome (IRIS) is an exaggerated 
      pathological inflammatory reaction which occurs after the initiation of the 
      antiretroviral therapy, due to the exuberant immune responses to the occult or 
      the apparent opportunistic infections. The hallmark of the syndrome is the 
      paradoxical worsening of an existing infection or a disease process or the 
      appearance of a new infection or a disease process soon after the initiation of 
      the antiretroviral therapy.The most common forms of IRIS occur in association 
      with tuberculosis and chronic viral and invasive fungal infections. Multiple IRIS 
      in a patient is extremely rare. Our patient had multiple manifestations of IRIS, 
      in the form of cryptococcal meningitis, toxoplasmosis and Cytomegalovirus (CMV) 
      retinitis after the initiation of highly active antiretroviral therapy.
FAU - Achappa, Basavaprabhu
AU  - Achappa B
AD  - Associate Professor, Department of General Medicine, Kasturba Medical College , 
      Mangalore, India.
FAU - Madi, Deepak
AU  - Madi D
FAU - Shetty, Nishitha
AU  - Shetty N
FAU - Mahalingam, Soundarya
AU  - Mahalingam S
LA  - eng
PT  - Case Reports
PL  - India
TA  - J Clin Diagn Res
JT  - Journal of clinical and diagnostic research : JCDR
JID - 101488993
PMC - PMC3527793
OTO - NOTNLM
OT  - Cryptococcal Meningitis
OT  - Cytomegalovirus (CMV) retinitis
OT  - HIV
OT  - Immune reconstitution inflammatory syndrome (IRIS)
OT  - Toxoplasmosis
EDAT- 2013/01/04 06:00
MHDA- 2013/01/04 06:01
PMCR- 2013/01/01
CRDT- 2013/01/04 06:00
PHST- 2012/06/12 00:00 [received]
PHST- 2012/10/05 00:00 [accepted]
PHST- 2013/01/04 06:00 [entrez]
PHST- 2013/01/04 06:00 [pubmed]
PHST- 2013/01/04 06:01 [medline]
PHST- 2013/01/01 00:00 [pmc-release]
AID - 10.7860/JCDR/2012/4547.2556 [doi]
PST - ppublish
SO  - J Clin Diagn Res. 2012 Nov;6(9):1547-9. doi: 10.7860/JCDR/2012/4547.2556.