PMID- 23285971
OWN - NLM
STAT- MEDLINE
DCOM- 20130826
LR  - 20190923
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 30
IP  - 9
DP  - 2012 Sep
TI  - [Direct determination of ethyl carbamate in Chinese rice wine and grape wine by 
      ultra performance liquid chromatography-electrospray ionization tandem mass 
      spectrometry].
PG  - 903-7
AB  - An ultra performance liquid chromatography-electrospray ionization tandem mass 
      spectrometric (UPLC-ESI-MS/MS) method was established for the direct 
      determination of ethyl carbamate in Chinese rice wine and grape wine. The Chinese 
      rice wine and grape wine samples were diluted with distilled water, filtered 
      through 0. 22 microm microporous membrane. The LC separation was performed on a 
      Waters Acquity UPLC system with a BEH C18 column, acetonitrile and 0. 1% (v/v) 
      acetic acid aqueous solution as the mobile phase. The ethyl carbamate was 
      determined in the mode of electrospray positive ionization (ESI+) and multiple 
      reaction monitoring (MRM). The butyl carbamate (BC) was used as the internal 
      standard for the quantitative determination. The calibration curve showed good 
      linearity in the range of 2 - 500 microg/L with the correlation coefficient 
      greater than 0.995. The limit of detection (LOD) was 1.7 microg/L and the limit 
      of quantification (LOQ) was 5.0 microg/L. The recoveries of the ethyl carbamate 
      in Chinese rice wine and grape wine was in the range of 90% - 102%. The relative 
      standard deviations (RSDs) of intra-day and inter-day determinations were 0. 8% - 
      4.5% and 1.4% - 5.6% (n = 6). The results indicated that the proposed method is 
      easy, fast, sensitive, and suitable for the determination of ethyl carbamate in 
      Chinese rice wine and grape wine.
FAU - Wang, Lijuan
AU  - Wang L
AD  - China National Research Institute of Food & Fermentation Industries, Beijing 
      100027, China.
FAU - Ke, Runhui
AU  - Ke R
FAU - Wang, Bing
AU  - Wang B
FAU - Yin, Jianjun
AU  - Yin J
FAU - Song, Quanhou
AU  - Song Q
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Carcinogens)
RN  - 3IN71E75Z5 (Urethane)
SB  - IM
MH  - Carcinogens/analysis
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Food Contamination/*analysis
MH  - Spectrometry, Mass, Electrospray Ionization/methods
MH  - Tandem Mass Spectrometry/*methods
MH  - Urethane/*analysis
MH  - Wine/*analysis
EDAT- 2013/01/05 06:00
MHDA- 2013/08/27 06:00
CRDT- 2013/01/05 06:00
PHST- 2013/01/05 06:00 [entrez]
PHST- 2013/01/05 06:00 [pubmed]
PHST- 2013/08/27 06:00 [medline]
AID - 10.3724/sp.j.1123.2012.05007 [doi]
PST - ppublish
SO  - Se Pu. 2012 Sep;30(9):903-7. doi: 10.3724/sp.j.1123.2012.05007.