PMID- 23286401
OWN - NLM
STAT- MEDLINE
DCOM- 20140130
LR  - 20130104
IS  - 1000-503X (Print)
IS  - 1000-503X (Linking)
VI  - 34
IP  - 6
DP  - 2012 Dec
TI  - [Association between cardiac function and intradialytic hypotension].
PG  - 573-9
LID - 10.3881/j.issn.1000-503X.2012.06.007 [doi]
AB  - OBJECTIVE: To prospectively determinate the association of left ventricular 
      systolic and diastolic function with intradialytic hypotension (IDH) in patients 
      on maintenance hemodialysis. METHODS: Totally 115 patients with sinus rhythm were 
      included in this study and divided into IDH group (n=29) and control group 
      (n=86). The cardiac function was assessed by New York Heart Association (NYHA) 
      classification before hemodialysis. Echocardiograms were performed in the next 
      day after hemodialysis and the software of GE EchoPAC was used to estimate 
      parameters of cardiac systolic and diastolic functions including ejection 
      fraction, fractional shortening of left ventricular diameter, stroke volume (SV), 
      cardiac output (CO), left ventricular mass index, Tei index, isovolumetric 
      relaxation time, E-deceleration time, mitral inflow peak early diastolic velocity 
      (E) to late diastolic velocities (A) ratio, and E to peak mitral annulus velocity 
      (E/Em) ratio. RESULTS: The mean age (p=0.045) and the ratio of heart failure 
      evaluated by the NYHA classification (p<0.01) were significantly higher in IDH 
      group than those in control group. No difference was noted for gender, body mass 
      index, duration of dialysis, body weight elevated rate and blood pressure between 
      these two groups (all p>0.05). Left ventricular diameters at the end of diastolic 
      phase, SV, and CO in IDH group were significantly lower than those in control 
      group (all P<0.05), whereas no significant difference was found for EF, FS, Tei 
      index, IVRT, EDT, E/A and E/Em ratio (all p>0.05). Multivariate logistic 
      regression analysis showed that NYHA cardiac function was an independent 
      predictor of IDH, and the risk of IDH increased by 1.134 times with incremental 
      one grade of NYHA classification. CONCLUSIONS: IDH is a common complication of 
      hemodialysis. Neither systolic dysfunction nor diastolic dysfunction of left 
      ventricle evaluated in second day after hemodialysis affects its frequency, 
      whereas the clinical cardiac function is an independent predictor of IDH.
FAU - Ye, Wen-ling
AU  - Ye WL
AD  - Department of Nephrology, PUMC Hospital, CAMS and PUMC, Beijing, China.
FAU - Fang, Li-gang
AU  - Fang LG
FAU - Ma, Jie
AU  - Ma J
FAU - Li, Xue-mei
AU  - Li XM
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Zhongguo Yi Xue Ke Xue Yuan Xue Bao
JT  - Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
JID - 8006230
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Case-Control Studies
MH  - Echocardiography
MH  - Female
MH  - Heart/*physiopathology
MH  - Humans
MH  - Hypotension/*etiology
MH  - Male
MH  - Middle Aged
MH  - Renal Dialysis/*adverse effects
MH  - Young Adult
EDAT- 2013/01/05 06:00
MHDA- 2014/01/31 06:00
CRDT- 2013/01/05 06:00
PHST- 2013/01/05 06:00 [entrez]
PHST- 2013/01/05 06:00 [pubmed]
PHST- 2014/01/31 06:00 [medline]
AID - 10.3881/j.issn.1000-503X.2012.06.007 [doi]
PST - ppublish
SO  - Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2012 Dec;34(6):573-9. doi: 
      10.3881/j.issn.1000-503X.2012.06.007.