PMID- 23292557
OWN - NLM
STAT- MEDLINE
DCOM- 20140116
LR  - 20211021
IS  - 1432-2218 (Electronic)
IS  - 0930-2794 (Linking)
VI  - 27
IP  - 6
DP  - 2013 Jun
TI  - Revisional laparoscopic antireflux surgery after unsuccessful endoscopic 
      fundoplication.
PG  - 2231-6
LID - 10.1007/s00464-012-2685-6 [doi]
AB  - BACKGROUND: Transoral incisionless fundoplication (TIF), a novel endoscopic 
      procedure for treating gastroesophageal reflux disease (GERD), currently is under 
      evaluation. In case of treatment failure, subsequent revisional laparoscopic 
      antireflux surgery (rLARS) may be required. This study aimed to evaluate the 
      feasibility, safety, and outcomes of revisional antireflux surgery after previous 
      endoscopic fundoplication. METHODS: Chronic GERD patients who underwent rLARS 
      after a previous TIF procedure were included in the study. Pre- and postoperative 
      assessment included GERD-related quality-of-life scores, proton pump inhibitor 
      (PPI) usage, 24-h pH-metry, upper gastrointestinal endoscopy, and registration of 
      adverse events. RESULTS: Revisional laparoscopic Nissen fundoplication was 
      feasible for all 15 patients included in the study without conversions to open 
      surgery. Acid exposure of the distal esophagus improved significantly after 
      rLARS, and esophagitis, PPI usage, and hiatal hernia decreased. Quality of life 
      did not improve significantly after rLARS, and 33 % of the patients experienced 
      dysphagia. CONCLUSION: Revisional laparoscopic Nissen fundoplication was feasible 
      and safe after unsuccessful endoscopic fundoplication, resulting in objective 
      reflux control at the cost of a relatively high rate of dysphagia.
FAU - Witteman, Bart P L
AU  - Witteman BP
AD  - Department of General Surgery, Maastricht University Medical Center, P. Debyelaan 
      25, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands. bplwitteman@gmail.com
FAU - Kessing, Boudewijn F
AU  - Kessing BF
FAU - Snijders, Gitte
AU  - Snijders G
FAU - Koek, Ger H
AU  - Koek GH
FAU - Conchillo, Jose M
AU  - Conchillo JM
FAU - Bouvy, Nicole D
AU  - Bouvy ND
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
DEP - 20130105
PL  - Germany
TA  - Surg Endosc
JT  - Surgical endoscopy
JID - 8806653
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
CIN - Surg Endosc. 2014 Apr;28(4):1382-3. PMID: 24162141
MH  - Adult
MH  - Aged
MH  - Deglutition Disorders/etiology
MH  - Endoscopy, Gastrointestinal/adverse effects/*methods
MH  - Feasibility Studies
MH  - Fundoplication/*methods
MH  - Gastroesophageal Reflux/drug therapy/*surgery
MH  - Humans
MH  - Laparoscopy/adverse effects/*methods
MH  - Middle Aged
MH  - Patient Satisfaction
MH  - Proton Pump Inhibitors/therapeutic use
MH  - Quality of Life
MH  - Reoperation
EDAT- 2013/01/08 06:00
MHDA- 2014/01/17 06:00
CRDT- 2013/01/08 06:00
PHST- 2012/06/17 00:00 [received]
PHST- 2012/10/25 00:00 [accepted]
PHST- 2013/01/08 06:00 [entrez]
PHST- 2013/01/08 06:00 [pubmed]
PHST- 2014/01/17 06:00 [medline]
AID - 10.1007/s00464-012-2685-6 [doi]
PST - ppublish
SO  - Surg Endosc. 2013 Jun;27(6):2231-6. doi: 10.1007/s00464-012-2685-6. Epub 2013 Jan 
      5.