PMID- 23297499 OWN - NLM STAT- MEDLINE DCOM- 20130624 LR - 20130109 IS - 1009-3591 (Print) IS - 1009-3591 (Linking) VI - 18 IP - 10 DP - 2012 Oct TI - [Etiologic factors of erectile dysfunction in men with type 2 diabetes mellitus]. PG - 904-8 AB - OBJECTIVE: To investigate the relationship of erectile dysfunction (ED) with blood vessel-, nerve- and androgen-related factors in young and middle-aged men with type 2 diabetes mellitus (T2DM) in order to provide some clinical evidence for early prevention and treatment of ED. METHODS: We divided 53 male T2DM patients under 50 years into an ED group (IIEF-5 score < or = 21, n = 28) and a non-ED (NED) group (IIEF-5 score > or = 22, n = 25). We detected the levels of blood lipid, glucose, total testosterone (TT), sex hormone-binding globulin (SHBG), sulfate dehydroepiandrosterone (DHEA-S), calculated free testosterone (cFT), and examined the complications of macroangiopathy (MA), diabetic retinopathy (DR) and diabetic peripheral neuropathy (DPN), and compared the above indicators between the two groups. RESULTS: There were no significant differences between the two groups in age, diabetes duration, body mass index, blood pressure, and blood lipid and glucose levels (P > 0.05). The incidence rate of DR was significantly higher in the ED than in the NED group (39.3% vs 4.0%, P < 0.05), but no statistically significant differences were found in the levels of TT, cFT, SHBG and DHEA-S and the incidence rates of MA and DPN between the two groups (P > 0.05). CONCLUSION: The incidence of ED is closely related to DR in young and middle-aged men with T2DM. Therefore particular attention should be paid to the erectile function of T2DM patients with DR as early as possible. FAU - Jiang, Xiao-Ping AU - Jiang XP AD - Department of Endocrinology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510120, China. jbzh852@sohu.com FAU - Li, Fang-Ping AU - Li FP FAU - Xuan, Xu-Jun AU - Xuan XJ FAU - Xiao, Hui-Sheng AU - Xiao HS FAU - Liu, Dan AU - Liu D FAU - Yan, Li AU - Yan L LA - chi PT - English Abstract PT - Journal Article PL - China TA - Zhonghua Nan Ke Xue JT - Zhonghua nan ke xue = National journal of andrology JID - 101093592 SB - IM MH - Adult MH - Diabetes Mellitus, Type 2/*complications MH - Diabetic Neuropathies/complications MH - Diabetic Retinopathy/*complications MH - Erectile Dysfunction/*etiology MH - Humans MH - Male MH - Middle Aged EDAT- 2013/01/10 06:00 MHDA- 2013/06/26 06:00 CRDT- 2013/01/10 06:00 PHST- 2013/01/10 06:00 [entrez] PHST- 2013/01/10 06:00 [pubmed] PHST- 2013/06/26 06:00 [medline] PST - ppublish SO - Zhonghua Nan Ke Xue. 2012 Oct;18(10):904-8.