PMID- 23303800
OWN - NLM
STAT- MEDLINE
DCOM- 20130325
LR  - 20130208
IS  - 1769-6917 (Electronic)
IS  - 0007-4551 (Linking)
VI  - 100
IP  - 1
DP  - 2013 Jan 1
TI  - [Diagnosis of brain metastases: an update in 2012].
PG  - 29-34
LID - 10.1684/bdc.2012.1677 [doi]
AB  - Diagnosis of brain metastases should aim to identify anatomoclinical entities for 
      which a specific treatment is more accurate. Growing numbers of targeted 
      therapies have shown to be effective against specific cancers. Several studies 
      have reported that targeted therapies are capable of reducing brain metastases in 
      melanoma or non small cell lung cancer (NSCLC), sometimes with a high dramatic 
      response. These results have clearly impacted routine neuropathological practice, 
      leading to multidisciplinary strategy management of brain metastases tissues. In 
      accordance with the recommendations of French National Cancer Institute (INCa), 
      the pathologist develops appropriate strategies for molecular and 
      immunohistochemical analysis, in order to provide results as soon as possible.
FAU - Lechapt-Zalcman, Emmanuele
AU  - Lechapt-Zalcman E
AD  - CHU de Caen, Laboratoire d'anatomie pathologique, avenue de la Cote-de-Nacre, 
      14033 Caen cedex 9, France. lechapt-e@chu-caen.fr
FAU - Karanian-Philippe, Marie
AU  - Karanian-Philippe M
FAU - Rousseau, Audrey
AU  - Rousseau A
LA  - fre
PT  - English Abstract
PT  - Journal Article
PT  - Review
TT  - Metastases cerebrales: role du pathologiste en 2012.
PL  - France
TA  - Bull Cancer
JT  - Bulletin du cancer
JID - 0072416
SB  - IM
MH  - Brain Neoplasms/genetics/*pathology/*secondary
MH  - Carcinoma, Non-Small-Cell Lung/pathology/secondary
MH  - Glioblastoma/pathology
MH  - Humans
MH  - Lung Neoplasms/pathology
MH  - Melanoma/genetics/pathology/secondary
MH  - Mutation
MH  - Neoplasms, Unknown Primary/pathology
OTO - NOTNLM
OT  - brain metastases
OT  - immunohistochemistry
OT  - pathobiology
OT  - targeted therapy
OT  - unknown primary site
EDAT- 2013/01/11 06:00
MHDA- 2013/03/26 06:00
CRDT- 2013/01/11 06:00
PHST- 2013/01/11 06:00 [entrez]
PHST- 2013/01/11 06:00 [pubmed]
PHST- 2013/03/26 06:00 [medline]
AID - S0007-4551(15)30281-2 [pii]
AID - 10.1684/bdc.2012.1677 [doi]
PST - ppublish
SO  - Bull Cancer. 2013 Jan 1;100(1):29-34. doi: 10.1684/bdc.2012.1677.