PMID- 23311715
OWN - NLM
STAT- MEDLINE
DCOM- 20130620
LR  - 20220318
IS  - 1939-1676 (Electronic)
IS  - 0891-6640 (Linking)
VI  - 27
IP  - 1
DP  - 2013 Jan-Feb
TI  - Comparison of force plate gait analysis and owner assessment of pain using the 
      Canine Brief Pain Inventory in dogs with osteoarthritis.
PG  - 22-30
LID - 10.1111/jvim.12004 [doi]
AB  - BACKGROUND: Lameness assessment using force plate gait analysis (FPGA) and owner 
      assessment of chronic pain using the Canine Brief Pain Inventory (CBPI) are valid 
      and reliable methods of evaluating canine osteoarthritis. There are no studies 
      comparing these 2 outcome measures. OBJECTIVE: Evaluate the relationship between 
      CBPI pain severity (PS) and interference (PI) scores with the vertical forces of 
      FPGA as efficacy measures in canine osteoarthritis. ANIMALS: Sixty-eight 
      client-owned dogs with osteoarthritis (50 hind limb and 18 forelimb). METHODS: 
      Double-blind, randomized. Owners completed the CBPI, and dogs underwent FPGA on 
      days 0 and 14. Dogs received carprofen or placebo on days 1 through 14. The 
      change in PS and PI scores from day 0 to 14 were compared to the change in peak 
      vertical force (PVF) and vertical impulse (VI). RESULTS: PS and PI scores 
      significantly decreased in carprofen- compared with placebo-treated dogs (P = 
      .002 and P = .03, respectively). PVF and VI significantly increased in carprofen- 
      compared with placebo-treated dogs (P = .006 and P = .02, respectively). There 
      was no correlation or concordance between the PS or PI score changes and change 
      in PVF or VI. CONCLUSIONS AND CLINICAL IMPORTANCE: In these dogs with hind limb 
      or forelimb osteoarthritis, owner assessment of chronic pain using the CBPI and 
      assessment of lameness using FPGA detected significant improvement in dogs 
      treated with carprofen. The lack of correlation or concordance between the change 
      in owner scores and vertical forces suggests that owners were focused on 
      behaviors other than lameness when making efficacy evaluations in their dogs.
CI  - Copyright (c) 2012 by the American College of Veterinary Internal Medicine.
FAU - Brown, D C
AU  - Brown DC
AD  - Department of Clinical Studies Veterinary Clinical Investigation Center, School 
      of Veterinary Medicine, Philadelphia, PA 19104-6010, USA. dottie@vet.upenn.edu
FAU - Boston, R C
AU  - Boston RC
FAU - Farrar, J T
AU  - Farrar JT
LA  - eng
GR  - 1-K08-DA-017720-02/DA/NIDA NIH HHS/United States
PT  - Comparative Study
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, N.I.H., Extramural
PL  - United States
TA  - J Vet Intern Med
JT  - Journal of veterinary internal medicine
JID - 8708660
RN  - 0 (Anti-Inflammatory Agents, Non-Steroidal)
RN  - 0 (Carbazoles)
RN  - FFL0D546HO (carprofen)
SB  - IM
MH  - Animals
MH  - Anti-Inflammatory Agents, Non-Steroidal/*therapeutic use
MH  - Carbazoles/*therapeutic use
MH  - Chronic Disease
MH  - Data Collection
MH  - Dog Diseases/*drug therapy/etiology
MH  - Dogs
MH  - Double-Blind Method
MH  - Forelimb
MH  - *Gait
MH  - Hindlimb
MH  - Humans
MH  - Lameness, Animal
MH  - Osteoarthritis/complications/drug therapy/*veterinary
MH  - Pain/drug therapy/etiology/*veterinary
MH  - Pain Measurement/veterinary
MH  - Surveys and Questionnaires
EDAT- 2013/01/15 06:00
MHDA- 2013/06/21 06:00
CRDT- 2013/01/15 06:00
PHST- 2012/04/05 00:00 [received]
PHST- 2012/09/12 00:00 [revised]
PHST- 2012/09/24 00:00 [accepted]
PHST- 2013/01/15 06:00 [entrez]
PHST- 2013/01/15 06:00 [pubmed]
PHST- 2013/06/21 06:00 [medline]
AID - 10.1111/jvim.12004 [doi]
PST - ppublish
SO  - J Vet Intern Med. 2013 Jan-Feb;27(1):22-30. doi: 10.1111/jvim.12004.