PMID- 23312880 OWN - NLM STAT- MEDLINE DCOM- 20140625 LR - 20141120 IS - 0013-7006 (Print) IS - 0013-7006 (Linking) VI - 39 IP - 5 DP - 2013 Oct TI - [The interest of maintenance electroconvulsive therapy in mood disorders]. PG - 367-73 LID - S0013-7006(12)00104-2 [pii] LID - 10.1016/j.encep.2012.06.010 [doi] AB - Maintenance electroconvulsive therapy (M-ECT) is a treatment indicated for the treatment and prevention of recurrent depression in patients who either do not respond or do not tolerate psychotropic medication. We evaluated, retrospectively, clinical response to a 6-month minimum course of M-ECT in 25 patients with a diagnosis of bipolar disorder or schizoaffective disorder according to DSM IV-TR criterion. Our study demonstrated a significant improvement of Global Assessment of functioning (GAF) scores after a six month minimum course of M-ECT (34.8 +/- 12.6 vs 65.6 +/- 10.8; P<0.05) as well as Brief Psychiatric Rating Scale scores (BPRS): 79.3 +/- 12.4 vs 43.4 +/- 10.2; P<0.05). We observed a slight increase of Mini Mental State Examination (MMSE) scores after M-ECT; nonetheless, it was not statistically significant (24.2 +/- 2.4 vs 26.2 +/- 2.4; P=0.2). Regarding the mean duration of hospitalizations, we showed a statistically significant decrease in the median number of days of hospitalization (72 [59-93.50] days before M-ECT vs 43 [25-76] days since the first M-ECT; P=0.017). Maintenance ECT allowed a significant improvement in psychiatric symptoms and global functioning of the patients included in this study, as well as a decrease in the number of days of hospitalization. However, our pattern is limited because of its small size; so, further prospective studies in this field, including larger population is highly recommended. CI - Copyright (c) 2013 L'Encephale, Paris. Published by Elsevier Masson SAS. All rights reserved. FAU - Zaki, H AU - Zaki H AD - Service hospitalo-universitaire de sante mentale et de therapeutique, faculte de medecine Paris-Descartes, universite Paris-Descartes, centre hospitalier Sainte-Anne, 7, rue Cabanis, 75674 Paris cedex 14, France. FAU - Sentissi, O AU - Sentissi O FAU - Olie, J-P AU - Olie JP FAU - Loo, H AU - Loo H FAU - Mouaffak, F AU - Mouaffak F FAU - Gaillard, R AU - Gaillard R LA - fre PT - English Abstract PT - Journal Article TT - Interet de l'electroconvulsivotherapie de maintenance dans les troubles de l'humeur. DEP - 20130111 PL - France TA - Encephale JT - L'Encephale JID - 7505643 RN - 0 (Psychotropic Drugs) SB - IM MH - Aged MH - Aged, 80 and over MH - Bipolar Disorder/diagnosis/psychology/*therapy MH - Combined Modality Therapy MH - Comorbidity MH - Depressive Disorder, Treatment-Resistant/diagnosis/psychology/*therapy MH - *Electroconvulsive Therapy MH - Female MH - Follow-Up Studies MH - Humans MH - Long-Term Care MH - Male MH - Middle Aged MH - Psychiatric Status Rating Scales MH - Psychotic Disorders/diagnosis/psychology/*therapy MH - Psychotropic Drugs/therapeutic use MH - Retrospective Studies MH - Secondary Prevention OTO - NOTNLM OT - Affective disorders OT - Continuation ECT OT - ECT de consolidation OT - ECT de maintenance OT - Electroconvulsivotherapy OT - Maintenance ECT OT - Schizoaffective disorders OT - Troubles de l'humeur OT - Troubles schizoaffectifs OT - Electroconvulsivotherapie EDAT- 2013/01/15 06:00 MHDA- 2014/06/26 06:00 CRDT- 2013/01/15 06:00 PHST- 2009/07/01 00:00 [received] PHST- 2012/03/29 00:00 [accepted] PHST- 2013/01/15 06:00 [entrez] PHST- 2013/01/15 06:00 [pubmed] PHST- 2014/06/26 06:00 [medline] AID - S0013-7006(12)00104-2 [pii] AID - 10.1016/j.encep.2012.06.010 [doi] PST - ppublish SO - Encephale. 2013 Oct;39(5):367-73. doi: 10.1016/j.encep.2012.06.010. Epub 2013 Jan 11.