PMID- 23314254
OWN - NLM
STAT- MEDLINE
DCOM- 20140128
LR  - 20211021
IS  - 1998-3689 (Electronic)
IS  - 0301-4738 (Print)
IS  - 0301-4738 (Linking)
VI  - 61
IP  - 5
DP  - 2013 May
TI  - Segmentation error and macular thickness measurements obtained with 
      spectral-domain optical coherence tomography devices in neovascular age-related 
      macular degeneration.
PG  - 213-7
LID - 10.4103/0301-4738.97075 [doi]
AB  - PURPOSE: To evaluate frequency and severity of segmentation errors of two 
      spectral-domain optical coherence tomography (SD-OCT) devices and error effect on 
      central macular thickness (CMT) measurements. MATERIALS AND METHODS: Twenty-seven 
      eyes of 25 patients with neovascular age-related macular degeneration, examined 
      using the Cirrus HD-OCT and Spectralis HRA + OCT, were retrospectively reviewed. 
      Macular cube 512 x 128 and 5-line raster scans were performed with the Cirrus and 
      512 x 25 volume scans with the Spectralis. Frequency and severity of segmentation 
      errors were compared between scans. RESULTS: Segmentation error frequency was 
      47.4% (baseline), 40.7% (1 month), 40.7% (2 months), and 48.1% (6 months) for the 
      Cirrus, and 59.3%, 62.2%, 57.8%, and 63.7%, respectively, for the Spectralis, 
      differing significantly between devices at all examinations (P < 0.05), except at 
      baseline. Average error score was 1.21 +/- 1.65 (baseline), 0.79 +/- 1.18 (1 month), 
      0.74 +/- 1.12 (2 months), and 0.96 +/- 1.11 (6 months) for the Cirrus, and 1.73 +/- 
      1.50, 1.54 +/- 1.35, 1.38 +/- 1.40, and 1.49 +/- 1.30, respectively, for the 
      Spectralis, differing significantly at 1 month and 2 months (P < 0.02). Automated 
      and manual CMT measurements by the Spectralis were larger than those by the 
      Cirrus. CONCLUSIONS: The Cirrus HD-OCT had a lower frequency and severity of 
      segmentation error than the Spectralis HRA + OCT. SD-OCT error should be 
      considered when evaluating retinal thickness.
FAU - Kim, Moosang
AU  - Kim M
AD  - Department of Ophthalmology, Kyung Hee University Hospital, Seoul, Korea.
FAU - Lee, Seung Jun
AU  - Lee SJ
FAU - Han, Jisang
AU  - Han J
FAU - Yu, Seung-Young
AU  - Yu SY
FAU - Kwak, Hyung Woo
AU  - Kwak HW
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - India
TA  - Indian J Ophthalmol
JT  - Indian journal of ophthalmology
JID - 0405376
SB  - IM
MH  - Aged
MH  - Female
MH  - Humans
MH  - Macula Lutea/*pathology
MH  - Macular Degeneration/complications/*diagnosis
MH  - Male
MH  - Retinal Neovascularization/*diagnosis/etiology
MH  - Retrospective Studies
MH  - Tomography, Optical Coherence/*methods
PMC - PMC3730504
COIS- Conflict of Interest: None declared.
EDAT- 2013/01/15 06:00
MHDA- 2014/01/29 06:00
PMCR- 2013/05/01
CRDT- 2013/01/15 06:00
PHST- 2013/01/15 06:00 [entrez]
PHST- 2013/01/15 06:00 [pubmed]
PHST- 2014/01/29 06:00 [medline]
PHST- 2013/05/01 00:00 [pmc-release]
AID - 97075 [pii]
AID - IJO-61-213 [pii]
AID - 10.4103/0301-4738.97075 [doi]
PST - ppublish
SO  - Indian J Ophthalmol. 2013 May;61(5):213-7. doi: 10.4103/0301-4738.97075.