PMID- 23320432
OWN - NLM
STAT- MEDLINE
DCOM- 20130814
LR  - 20191112
IS  - 2212-3911 (Electronic)
IS  - 1574-8863 (Linking)
VI  - 7
IP  - 5
DP  - 2012 Nov 1
TI  - Isolated unilateral tongue oedema: the adverse effect of Angiotensin converting 
      enzyme inhibitors.
PG  - 382-3
AB  - Angiotensin converting enzyme inhibitors (ACEI) are widely used to treat benign 
      hypertension. These drugs are generally well tolerated. Serious side effects such 
      as angio-oedema are very rare. The authors report a 64-year-old Caucasian woman 
      with a history of liver transplant on Mammalian Target Of Rapamycin (mTOR) 
      inhibitor, who attended Emergency department with angio-oedema only on the left 
      side of her tongue. Her airway was patent and she was haemodynamically stable. 
      Trauma was denied. Her physician had 2 days earlier commenced her on Lisinopril 
      for newly diagnosed benign hypertension. Intravenous steroids and anti-histamine 
      were immediately administered. A good response of oedema subsidence was noted. In 
      general, angio-oedema can present in a spectrum of severity. Precipitating 
      factors are often difficult to pre-determine and avoid. Early recognition of risk 
      factors for and diagnosis of angio-oedema can often be life-saving.
FAU - Leung, Edmund
AU  - Leung E
AD  - University Hospitals Coventry and Warwickshire, Warwick, UK. 
      ed.leung@doctors.org.uk
FAU - Hanna, Marcelino Yazbek
AU  - Hanna MY
FAU - Tehami, Nadeem
AU  - Tehami N
FAU - Francombe, James
AU  - Francombe J
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United Arab Emirates
TA  - Curr Drug Saf
JT  - Current drug safety
JID - 101270895
RN  - 0 (Angiotensin-Converting Enzyme Inhibitors)
RN  - E7199S1YWR (Lisinopril)
SB  - IM
MH  - Angioedema/*chemically induced
MH  - Angiotensin-Converting Enzyme Inhibitors/*adverse effects
MH  - Female
MH  - Humans
MH  - Lisinopril/*adverse effects
MH  - Middle Aged
MH  - Tongue Diseases/*chemically induced
EDAT- 2013/01/17 06:00
MHDA- 2013/08/15 06:00
CRDT- 2013/01/17 06:00
PHST- 2012/08/24 00:00 [received]
PHST- 2012/11/16 00:00 [revised]
PHST- 2013/01/07 00:00 [accepted]
PHST- 2013/01/17 06:00 [entrez]
PHST- 2013/01/17 06:00 [pubmed]
PHST- 2013/08/15 06:00 [medline]
AID - CDS-EPUB-20130116-2 [pii]
AID - 10.2174/157488612805076561 [doi]
PST - ppublish
SO  - Curr Drug Saf. 2012 Nov 1;7(5):382-3. doi: 10.2174/157488612805076561.