PMID- 23325820
OWN - NLM
STAT- MEDLINE
DCOM- 20130904
LR  - 20211021
IS  - 1098-660X (Electronic)
IS  - 0095-1137 (Print)
IS  - 0095-1137 (Linking)
VI  - 51
IP  - 4
DP  - 2013 Apr
TI  - Evaluation of Epstein-Barr virus, human herpesvirus 6 (HHV-6), and HHV-8 
      antiviral drug susceptibilities by use of real-time-PCR-based assays.
PG  - 1244-6
LID - 10.1128/JCM.03234-12 [doi]
AB  - Evaluation of candidate antiviral drugs against Epstein-Barr virus (EBV), human 
      herpesvirus 6 (HHV-6), and HHV-8 is hampered by the lack of convenient laboratory 
      assays. We developed real-time quantitative PCR assays performed on supernatants 
      of lymphoma cell lines and determined the 50% inhibitory concentrations (IC50s) 
      of nucleoside, nucleotide, and pyrophosphate analogues against these 
      herpesviruses.
FAU - Bounaadja, Lotfi
AU  - Bounaadja L
AD  - Infectious Disease Research Centre, Laval University, Quebec City, Quebec, 
      Canada.
FAU - Piret, Jocelyne
AU  - Piret J
FAU - Goyette, Nathalie
AU  - Goyette N
FAU - Boivin, Guy
AU  - Boivin G
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130116
PL  - United States
TA  - J Clin Microbiol
JT  - Journal of clinical microbiology
JID - 7505564
RN  - 0 (Antiviral Agents)
SB  - IM
CIN - J Clin Microbiol. 2013 Jun;51(6):2013. PMID: 23682102
CIN - J Clin Microbiol. 2013 Jun;51(6):2014. PMID: 23682103
MH  - Antiviral Agents/*pharmacology
MH  - Cell Line, Tumor
MH  - Herpesvirus 4, Human/*drug effects
MH  - Herpesvirus 6, Human/*drug effects
MH  - Herpesvirus 8, Human/*drug effects
MH  - Humans
MH  - Inhibitory Concentration 50
MH  - Microbial Sensitivity Tests/methods
MH  - Real-Time Polymerase Chain Reaction/*methods
PMC - PMC3666796
EDAT- 2013/01/18 06:00
MHDA- 2013/09/05 06:00
PMCR- 2013/10/01
CRDT- 2013/01/18 06:00
PHST- 2013/01/18 06:00 [entrez]
PHST- 2013/01/18 06:00 [pubmed]
PHST- 2013/09/05 06:00 [medline]
PHST- 2013/10/01 00:00 [pmc-release]
AID - JCM.03234-12 [pii]
AID - 03234-12 [pii]
AID - 10.1128/JCM.03234-12 [doi]
PST - ppublish
SO  - J Clin Microbiol. 2013 Apr;51(4):1244-6. doi: 10.1128/JCM.03234-12. Epub 2013 Jan 
      16.