PMID- 23327971
OWN - NLM
STAT- MEDLINE
DCOM- 20130711
LR  - 20190902
IS  - 1881-7742 (Electronic)
IS  - 0301-4800 (Linking)
VI  - 58
IP  - 5
DP  - 2012
TI  - Impact of intensive high-fat ingestion in the early stage of recovery from 
      exercise training on substrate metabolism during exercise in humans.
PG  - 354-9
AB  - Not only increasing body carbohydrate (CHO) stores before exercise but also 
      suppressing CHO oxidation during exercise is important for improving endurance 
      performance. We tested the hypothesis that intensive high-fat ingestion in the 
      early stage of recovery from exercise training (ET) for 2 d would suppress CHO 
      oxidation during exercise by increasing whole body lipolysis and/or fat 
      oxidation. In a randomized crossover design, on days 1 and 2, six male subjects 
      performed cycle ET at 50% peak oxygen consumption (VO(2 peak)) for 60-90 min, and 
      consumed a control diet (CON: 1,224 kcal, 55% carbohydrate, 30% fat) or the same 
      diet supplemented with high fat (HF: 1,974 kcal, 34% carbohydrate, 56% fat) 1 h 
      after ET, with the diet other than post-ET similar in both trials. On day 3, 
      subjects performed cycle exercise at 65% VO(2 peak) until exhaustion. Exercise 
      time to exhaustion was longer in the HF trial than in the CON trial (CON: 48.9 +/- 
      6.7 vs. HF: 55.8 +/- 7.7 min, p<0.05). In the HF trial, total fat oxidation until 
      exhaustion was higher, accompanied by higher post-exercise plasma glycerol 
      concentration, than in the CON trial (CON: 213 +/- 54 vs. HF: 286 +/- 63 kcal, 
      p<0.05), whereas total carbohydrate oxidation until exhaustion was not different 
      between trials. These results suggest that intensive high-fat ingestion in the 
      early stage of recovery from ET for a few days until the day before exercise was 
      an effective means of eliciting a CHO-sparing effect during exercise by enhancing 
      fat metabolism.
FAU - Ichinose, Takashi
AU  - Ichinose T
AD  - Faculty of Human Sciences, Waseda University, Tokorozawa, Japan. 
      icchi@fuji.waseda.jp
FAU - Arai, Natsuko
AU  - Arai N
FAU - Nagasaka, Tomoaki
AU  - Nagasaka T
FAU - Asano, Masaya
AU  - Asano M
FAU - Hashimoto, Kenji
AU  - Hashimoto K
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - Japan
TA  - J Nutr Sci Vitaminol (Tokyo)
JT  - Journal of nutritional science and vitaminology
JID - 0402640
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Fats)
RN  - 0 (Insulin)
RN  - 0 (Triglycerides)
RN  - PDC6A3C0OX (Glycerol)
SB  - IM
MH  - Blood Glucose/analysis
MH  - Body Height
MH  - Body Mass Index
MH  - Body Weight
MH  - *Carbohydrate Metabolism
MH  - Cross-Over Studies
MH  - Diet
MH  - Dietary Carbohydrates/administration & dosage
MH  - Dietary Fats/*administration & dosage
MH  - Exercise/*physiology
MH  - Glycerol/blood
MH  - Humans
MH  - Insulin/blood
MH  - Lipolysis
MH  - Male
MH  - Oxygen Consumption
MH  - Triglycerides/analysis
MH  - Young Adult
EDAT- 2013/01/19 06:00
MHDA- 2013/07/13 06:00
CRDT- 2013/01/19 06:00
PHST- 2013/01/19 06:00 [entrez]
PHST- 2013/01/19 06:00 [pubmed]
PHST- 2013/07/13 06:00 [medline]
AID - DN/JST.JSTAGE/jnsv/58.354 [pii]
AID - 10.3177/jnsv.58.354 [doi]
PST - ppublish
SO  - J Nutr Sci Vitaminol (Tokyo). 2012;58(5):354-9. doi: 10.3177/jnsv.58.354.