PMID- 23332232 OWN - NLM STAT- MEDLINE DCOM- 20130828 LR - 20220408 IS - 1873-2380 (Electronic) IS - 0021-9290 (Print) IS - 0021-9290 (Linking) VI - 46 IP - 5 DP - 2013 Mar 15 TI - Micro and nano MgO particles for the improvement of fracture toughness of bone-cement interfaces. PG - 1035-9 LID - S0021-9290(12)00731-2 [pii] LID - 10.1016/j.jbiomech.2012.12.006 [doi] AB - The objective of this study was to determine whether inclusion of magnesium oxide (MgO) in micro and nanoparticulate forms in poly methyl methacrylate (PMMA) cement has any influence on the fracture toughness of bone-cement interfaces. An interfacial fracture mechanics technique was used to compare the values of fracture toughness (KIC) among bone-PMMA, bone-PMMA with micro MgO particles and bone-PMMA with nano MgO particles interfaces. This study found that the values of KIC of bone-PMMA with micro MgO particles and bone-PMMA with nano MgO particles interfaces were significantly higher when compared to the values of KIC of the bone-PMMA interface (p<0.0001). Results indicated that the addition of the micro and nano MgO particles to PMMA improved the quality of bone-cement union. CI - Copyright (c) 2012 Elsevier Ltd. All rights reserved. FAU - Khandaker, Morshed AU - Khandaker M AD - Department of Engineering & Physics, University of Central Oklahoma, Edmond, OK 73034, USA. mkhandaker@uco.edu FAU - Li, Yanling AU - Li Y FAU - Morris, Tracy AU - Morris T LA - eng GR - P20 GM103447/GM/NIGMS NIH HHS/United States GR - P20 RR016478/RR/NCRR NIH HHS/United States GR - P2PRR016478/PHS HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural DEP - 20130116 PL - United States TA - J Biomech JT - Journal of biomechanics JID - 0157375 RN - 0 (Bone Cements) RN - 3A3U0GI71G (Magnesium Oxide) RN - 9011-14-7 (Polymethyl Methacrylate) SB - IM MH - Animals MH - Bone Cements/*chemistry MH - Cattle MH - Femoral Fractures/*pathology/*therapy MH - Femur/*pathology MH - Magnesium Oxide/*chemistry MH - Nanoparticles/*chemistry MH - Polymethyl Methacrylate/chemistry PMC - PMC3594577 MID - NIHMS431757 COIS- 6. Conflict of interest The authors have no conflict of interest. EDAT- 2013/01/22 06:00 MHDA- 2013/08/29 06:00 PMCR- 2014/03/15 CRDT- 2013/01/22 06:00 PHST- 2012/05/31 00:00 [received] PHST- 2012/10/30 00:00 [revised] PHST- 2012/12/12 00:00 [accepted] PHST- 2013/01/22 06:00 [entrez] PHST- 2013/01/22 06:00 [pubmed] PHST- 2013/08/29 06:00 [medline] PHST- 2014/03/15 00:00 [pmc-release] AID - S0021-9290(12)00731-2 [pii] AID - 10.1016/j.jbiomech.2012.12.006 [doi] PST - ppublish SO - J Biomech. 2013 Mar 15;46(5):1035-9. doi: 10.1016/j.jbiomech.2012.12.006. Epub 2013 Jan 16.