PMID- 23338247 OWN - NLM STAT- MEDLINE DCOM- 20130801 LR - 20211021 IS - 1432-2102 (Electronic) IS - 0033-832X (Linking) VI - 53 IP - 1 DP - 2013 Jan TI - [MRI for myocarditis]. PG - 30-7 LID - 10.1007/s00117-012-2385-1 [doi] AB - Cardiovascular magnetic resonance imaging (CMRI) has become the primary tool for the non-invasive assessment in patients with suspected myocarditis, especially after exclusion of acute coronary syndrome (ACS) for the differential diagnosis. Various MRI parameters are available which have different accuracies. Volumetric and functional ventricular assessment and the occurrence of pericardial effusion alone demonstrate only a poor sensitivity and specificity. The calculation of the T2-ratio (edema assessment), the early or global relative myocardial enhancement (gRE) and the late gadolinium enhancement (LGE), which represents irreversibly injured myocardium, are more specific parameters. All MRI parameters demonstrate the best accuracy in infarct-like acute myocarditis, whereas in chronic myocarditis sensitivity and specificity are less accurate. Therefore, a multisequential (at least two out of three parameters are positive) approach is recommended. The assessment of the value of newer, more quantitative MRI sequences, such as T1 and T2-mapping is still under investigation. FAU - Gutberlet, M AU - Gutberlet M AD - Abteilung fur Diagnostische und Interventionelle Radiologie, Herzzentrum, Universitat Leipzig, Deutschland. matthias.gutberlet@herzzentrum-leipzig.de FAU - Lucke, C AU - Lucke C FAU - Krieghoff, C AU - Krieghoff C FAU - Hildebrand, L AU - Hildebrand L FAU - Lurz, P AU - Lurz P FAU - Steiner, J AU - Steiner J FAU - Adam, J AU - Adam J FAU - Eitel, I AU - Eitel I FAU - Thiele, H AU - Thiele H FAU - Grothoff, M AU - Grothoff M FAU - Lehmkuhl, L AU - Lehmkuhl L LA - ger PT - English Abstract PT - Journal Article TT - MRT bei Myokarditis. PL - Germany TA - Radiologe JT - Der Radiologe JID - 0401257 SB - IM EIN - Radiologe. 2013 Apr;53(4):335. Grotthoff, M [corrected to Grothoff, M] MH - Humans MH - Image Enhancement/*methods MH - Magnetic Resonance Imaging, Cine/*methods MH - Myocarditis/*diagnosis MH - Reproducibility of Results MH - Sensitivity and Specificity MH - *Stroke Volume EDAT- 2013/01/23 06:00 MHDA- 2013/08/02 06:00 CRDT- 2013/01/23 06:00 PHST- 2013/01/23 06:00 [entrez] PHST- 2013/01/23 06:00 [pubmed] PHST- 2013/08/02 06:00 [medline] AID - 10.1007/s00117-012-2385-1 [doi] PST - ppublish SO - Radiologe. 2013 Jan;53(1):30-7. doi: 10.1007/s00117-012-2385-1.