PMID- 23338929 OWN - NLM STAT- MEDLINE DCOM- 20131223 LR - 20130122 IS - 2737-5935 (Electronic) IS - 0037-5675 (Linking) VI - 54 IP - 1 DP - 2013 Jan TI - Percutaneous mitral valve repair with MitraClip for severe functional mitral regurgitation. PG - e9-e12 AB - A 67-year-old Chinese woman with comorbidities of chronic obstructive lung disease, hypertension and prior coronary artery bypass surgery presented with severe functional mitral regurgitation (MR) and severely depressed left ventricular function. She was in New York Heart Association (NYHA) Class II-III. Due to high surgical risk, she was referred for percutaneous treatment with the MitraClip valve repair system. This procedure is typically performed via the femoral venous system and involves a transseptal puncture. A clip is delivered to grasp the regurgitant mitral valve leaflets and reduce MR. This was performed uneventfully in our patient, with reduction of MR from 4+ to 1+. She was discharged on post-procedure Day 2 and her NYHA class improved to Class I. This was the first successful MitraClip procedure performed in Asia and represents a valuable treatment option in patients with severe MR, especially those with functional MR or those at high surgical risk. FAU - Yeo, Khung Keong AU - Yeo KK AD - Department of Cardiology, National Heart Centre, Singapore. yeo.khung.keong@nhcs.com.sg FAU - Ding, Zee Pin AU - Ding ZP FAU - Chua, Yeow Leng AU - Chua YL FAU - Lim, Soo Teik AU - Lim ST FAU - Sin, Kenny Yoong Kong AU - Sin KY FAU - Tan, Jack Wei Chieh AU - Tan JW FAU - Chiam, Paul Toon Lim AU - Chiam PT FAU - Hwang, Nian Chih AU - Hwang NC FAU - Koh, Tian Hai AU - Koh TH LA - eng PT - Case Reports PT - Journal Article PL - India TA - Singapore Med J JT - Singapore medical journal JID - 0404516 SB - IM MH - Aged MH - Cardiac Surgical Procedures/*methods MH - Cardiology/*instrumentation/methods MH - *Catheters MH - Echocardiography/methods MH - Equipment and Supplies MH - Female MH - Heart Ventricles/physiopathology MH - Humans MH - Mitral Valve/*surgery MH - Mitral Valve Insufficiency/*surgery MH - Pulmonary Disease, Chronic Obstructive/complications MH - Risk MH - Ultrasonography, Doppler/methods MH - Ventricular Dysfunction, Left/surgery EDAT- 2013/01/23 06:00 MHDA- 2013/12/24 06:00 CRDT- 2013/01/23 06:00 PHST- 2013/01/23 06:00 [entrez] PHST- 2013/01/23 06:00 [pubmed] PHST- 2013/12/24 06:00 [medline] PST - ppublish SO - Singapore Med J. 2013 Jan;54(1):e9-e12.