PMID- 23341840 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20130124 LR - 20211021 IS - 1671-5411 (Print) IS - 1671-5411 (Linking) VI - 9 IP - 4 DP - 2012 Dec TI - Chronic kidney disease: an independent risk factor of all-cause mortality for elderly Chinese patients with chronic heart failure. PG - 355-60 LID - 10.3724/SP.J.1263.2012.04121 [doi] AB - OBJECTIVE: To evaluate the prognostic value of chronic kidney disease (CKD) in elderly Chinese patients with chronic heart failure (CHF). METHODS: The study consisted of 327 elderly patients with CHF. All-cause mortality was chosen as an endpoint over the median follow-up period of 345 days. Cox regression analysis was used to identify the risk factors of mortality. RESULTS: The median age of the entire cohort was 85 years (60-100 years). The mortality for 168 elderly patients with CHF and CKD (51.4% of entire cohort) was 39.9% (67 deaths), which was higher than the mortality for CHF patients without CKD [25.2% (40/159 deaths)] and the mortality for entire cohort with CHF [32.7% (107/327 deaths)]. The Cox regression analysis showed that old age [hazard ratio (HR): 1.033; 95% confidence interval (95% CI): 1.004-1.064], CKD (HR: 1.705; 95% CI: 1.132-2.567), CHF New York Heart Association (NYHA) class IV (HR: 1.913; 95% CI: 1.284-2.851), acute myocardial infarction (AMI) (HR: 1.696; 95% CI: 1.036-2.777), elevated resting heart rate (HR: 1.021; 95% CI: 1.009-1.033), and decreased plasma albumin (HR: 0.883; 95% CI: 0.843-0.925) were independent risk factors of mortality for elderly patients with CHF. CONCLUSIONS: CKD was an independent risk factor of mortality for elderly Chinese patients with CHF. FAU - Fu, Shi-Hui AU - Fu SH AD - Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing 100853, China. FAU - Zhu, Bing AU - Zhu B FAU - Zhang, Yu-Xiao AU - Zhang YX FAU - Yi, Shuang-Yan AU - Yi SY FAU - Liu, Yuan AU - Liu Y FAU - Xiao, Tie-Hui AU - Xiao TH FAU - Wang, Liang AU - Wang L FAU - Bai, Yong-Yi AU - Bai YY FAU - Lu, Cai-Yi AU - Lu CY FAU - Ye, Ping AU - Ye P FAU - Luo, Lei-Ming AU - Luo LM LA - eng PT - Journal Article PL - China TA - J Geriatr Cardiol JT - Journal of geriatric cardiology : JGC JID - 101237881 PMC - PMC3545252 OTO - NOTNLM OT - Chronic heart failure OT - Chronic kidney disease OT - Risk factor OT - The aged EDAT- 2013/01/24 06:00 MHDA- 2013/01/24 06:01 PMCR- 2012/12/01 CRDT- 2013/01/24 06:00 PHST- 2012/04/12 00:00 [received] PHST- 2012/12/06 00:00 [revised] PHST- 2012/12/12 00:00 [accepted] PHST- 2013/01/24 06:00 [entrez] PHST- 2013/01/24 06:00 [pubmed] PHST- 2013/01/24 06:01 [medline] PHST- 2012/12/01 00:00 [pmc-release] AID - jgc-09-04-355 [pii] AID - 10.3724/SP.J.1263.2012.04121 [doi] PST - ppublish SO - J Geriatr Cardiol. 2012 Dec;9(4):355-60. doi: 10.3724/SP.J.1263.2012.04121.