PMID- 23342481 OWN - NLM STAT- MEDLINE DCOM- 20130212 LR - 20130123 IS - 0012-7183 (Print) IS - 0012-7183 (Linking) VI - 128 IP - 22 DP - 2012 TI - [Multiple endocrine neoplasia type 1]. PG - 2345-54 AB - Multiple endocrine neoplasia type 1 (MEN1) is a complex multisystem disease characterized by the combined occurrence of endocrine tumours of the parathyroid glands, anterior pituitary gland and adrenal glands and the neuroendocrine tumours (NET) of duodenum, pancreas, thymus and bronchus. Malignancy occurs commonly (up to 30 %) and malignant NETs are important causes of the MEN1-related morbidity and mortality. Regular clinical, biochemical and radiologic screening for the syndrome-related tumours are the basis of the life-long surveillance. Early detection and adequate management of these tumours reduce risk of death and morbidity. FAU - Salmela, Pasi I AU - Salmela PI AD - OYS, medisiininen tulosalue, sisatautien ja keuhkosairauksien vastuualue. LA - fin PT - English Abstract PT - Journal Article PT - Review TT - Tyypin 1 multippeli endokriininen neoplasia eli MEN 1-oireyhtymi. PL - Finland TA - Duodecim JT - Duodecim; laaketieteellinen aikakauskirja JID - 0373207 SB - IM MH - Early Diagnosis MH - Humans MH - Multiple Endocrine Neoplasia Type 1/*diagnosis/mortality/pathology EDAT- 2013/01/25 06:00 MHDA- 2013/02/13 06:00 CRDT- 2013/01/25 06:00 PHST- 2013/01/25 06:00 [entrez] PHST- 2013/01/25 06:00 [pubmed] PHST- 2013/02/13 06:00 [medline] PST - ppublish SO - Duodecim. 2012;128(22):2345-54.