PMID- 23343014
OWN - NLM
STAT- MEDLINE
DCOM- 20130725
LR  - 20220318
IS  - 1476-069X (Electronic)
IS  - 1476-069X (Linking)
VI  - 12
DP  - 2013 Jan 23
TI  - Environmental exposure assessment in European birth cohorts: results from the 
      ENRIECO project.
PG  - 8
LID - 10.1186/1476-069X-12-8 [doi]
AB  - Environmental exposures during pregnancy and early life may have adverse health 
      effects. Single birth cohort studies often lack statistical power to tease out 
      such effects reliably. To improve the use of existing data and to facilitate 
      collaboration among these studies, an inventory of the environmental exposure and 
      health data in these studies was made as part of the ENRIECO (Environmental 
      Health Risks in European Birth Cohorts) project. The focus with regard to 
      exposure was on outdoor air pollution, water contamination, allergens and 
      biological organisms, metals, pesticides, smoking and second hand tobacco smoke 
      (SHS), persistent organic pollutants (POPs), noise, radiation, and occupational 
      exposures. The review lists methods and data on environmental exposures in 37 
      European birth cohort studies. Most data is currently available for smoking and 
      SHS (N=37 cohorts), occupational exposures (N=33), outdoor air pollution, and 
      allergens and microbial agents (N=27). Exposure modeling is increasingly used for 
      long-term air pollution exposure assessment; biomonitoring is used for assessment 
      of exposure to metals, POPs and other chemicals; and environmental monitoring for 
      house dust mite exposure assessment. Collaborative analyses with data from 
      several birth cohorts have already been performed successfully for outdoor air 
      pollution, water contamination, allergens, biological contaminants, molds, POPs 
      and SHS. Key success factors for collaborative analyses are common definitions of 
      main exposure and health variables. Our review emphasizes that such common 
      definitions need ideally be arrived at in the study design phase. However, 
      careful comparison of methods used in existing studies also offers excellent 
      opportunities for collaborative analyses. Investigators can use this review to 
      evaluate the potential for future collaborative analyses with respect to data 
      availability and methods used in the different cohorts and to identify potential 
      partners for a specific research question.
FAU - Gehring, Ulrike
AU  - Gehring U
AD  - Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The 
      Netherlands. u.gehring@uu.nl
FAU - Casas, Maribel
AU  - Casas M
FAU - Brunekreef, Bert
AU  - Brunekreef B
FAU - Bergstrom, Anna
AU  - Bergstrom A
FAU - Bonde, Jens Peter
AU  - Bonde JP
FAU - Botton, Jeremie
AU  - Botton J
FAU - Chevrier, Cecile
AU  - Chevrier C
FAU - Cordier, Sylvaine
AU  - Cordier S
FAU - Heinrich, Joachim
AU  - Heinrich J
FAU - Hohmann, Cynthia
AU  - Hohmann C
FAU - Keil, Thomas
AU  - Keil T
FAU - Sunyer, Jordi
AU  - Sunyer J
FAU - Tischer, Christina G
AU  - Tischer CG
FAU - Toft, Gunnar
AU  - Toft G
FAU - Wickman, Magnus
AU  - Wickman M
FAU - Vrijheid, Martine
AU  - Vrijheid M
FAU - Nieuwenhuijsen, Mark
AU  - Nieuwenhuijsen M
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20130123
PL  - England
TA  - Environ Health
JT  - Environmental health : a global access science source
JID - 101147645
RN  - 0 (Allergens)
RN  - 0 (Environmental Pollutants)
SB  - IM
MH  - Allergens/toxicity
MH  - *Cohort Studies
MH  - Electromagnetic Fields/adverse effects
MH  - *Environmental Exposure
MH  - Environmental Health/methods
MH  - Environmental Monitoring
MH  - Environmental Pollutants/toxicity
MH  - Europe/epidemiology
MH  - Female
MH  - Humans
MH  - Models, Theoretical
MH  - Pregnancy
MH  - Prenatal Exposure Delayed Effects/*epidemiology/*etiology
MH  - Risk Assessment
PMC - PMC3564791
EDAT- 2013/01/25 06:00
MHDA- 2013/07/26 06:00
PMCR- 2013/01/23
CRDT- 2013/01/25 06:00
PHST- 2012/06/29 00:00 [received]
PHST- 2013/01/08 00:00 [accepted]
PHST- 2013/01/25 06:00 [entrez]
PHST- 2013/01/25 06:00 [pubmed]
PHST- 2013/07/26 06:00 [medline]
PHST- 2013/01/23 00:00 [pmc-release]
AID - 1476-069X-12-8 [pii]
AID - 10.1186/1476-069X-12-8 [doi]
PST - epublish
SO  - Environ Health. 2013 Jan 23;12:8. doi: 10.1186/1476-069X-12-8.