PMID- 23350726
OWN - NLM
STAT- MEDLINE
DCOM- 20131230
LR  - 20220408
IS  - 1463-1326 (Electronic)
IS  - 1462-8902 (Print)
IS  - 1462-8902 (Linking)
VI  - 15
IP  - 6
DP  - 2013 Jun
TI  - A nine country study of the burden of non-severe nocturnal hypoglycaemic events 
      on diabetes management and daily function.
PG  - 546-57
LID - 10.1111/dom.12070 [doi]
AB  - AIMS: The purpose of this study was to explore the burden and impact of 
      non-severe nocturnal hypoglycaemic events (NSNHEs) on diabetes management, 
      patient functioning and well-being in order to better understand the role that 
      NSNHEs play in caring for persons with diabetes and facilitate optimal diabetes 
      treatment management strategies. METHODS: A 20-min survey assessing the impact of 
      NSNHEs was administered to patients with self-reported diabetes age 18 or older 
      via the Internet in nine countries (USA, UK, Germany, Canada, France, Italy, 
      Spain, The Netherlands and Sweden) who experienced an NSNHE in the last month. 
      Questions captured reasons for and length of the event, and impacts on diabetes 
      management, daily function, sleep and well-being. RESULTS: A total of 20 212 
      persons with Type 1 diabetes mellitus (T1DM) and Type 2 diabetes mellitus (T2DM) 
      were screened of which 2108 respondents were eligible. Respondents initiated, on 
      average, an additional 3.6 glucose monitoring tests, and did not resume usual 
      functioning for an average of 3.4 hours after the NSNHE. Of the respondents using 
      insulin, 15.8% decreased their insulin dose over an average of 3.6 days. NSNHEs 
      also impacted sleep, with 10.4% not returning to sleep that night. Next day 
      functioning was affected with 60.3% (n = 1273) feeling the need to take a nap 
      and/or rest (with 65.5% of those actually taking a nap/rest) and 40.2% (n = 848) 
      wanting to go to bed earlier than usual. A total of 21.4% were restricted in 
      their driving the next day. These events also resulted in decreased well-being 
      with 39.6% of respondents feeling 'emotional low' the following day. CONCLUSIONS: 
      NSNHEs have serious consequences for patients. Greater attention to patient and 
      physician education regarding the burden of NSNHEs and incorporation of 
      corrective actions in treatment plans is needed to facilitate patients reaching 
      optimal glycaemic control.
CI  - (c) 2013 Blackwell Publishing Ltd.
FAU - Brod, M
AU  - Brod M
AD  - The Brod Group, Mill Valley, CA 94941, USA. mbrod@thebrodgroup.net
FAU - Wolden, M
AU  - Wolden M
FAU - Christensen, T
AU  - Christensen T
FAU - Bushnell, D M
AU  - Bushnell DM
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20130225
PL  - England
TA  - Diabetes Obes Metab
JT  - Diabetes, obesity & metabolism
JID - 100883645
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Blood Glucose Self-Monitoring/*statistics & numerical data
MH  - Canada/epidemiology
MH  - Circadian Rhythm
MH  - Diabetes Mellitus, Type 1/blood/*epidemiology/psychology
MH  - Diabetes Mellitus, Type 2/blood/*epidemiology/psychology
MH  - Female
MH  - France/epidemiology
MH  - Germany/epidemiology
MH  - Humans
MH  - Hypoglycemia/blood/*epidemiology/psychology
MH  - Italy/epidemiology
MH  - Male
MH  - Middle Aged
MH  - Netherlands/epidemiology
MH  - Online Systems
MH  - Outcome Assessment, Health Care
MH  - Population Surveillance
MH  - *Quality of Life
MH  - Severity of Illness Index
MH  - Sickness Impact Profile
MH  - Spain/epidemiology
MH  - Sweden/epidemiology
MH  - United Kingdom/epidemiology
MH  - United States/epidemiology
PMC - PMC3662999
EDAT- 2013/01/29 06:00
MHDA- 2014/01/01 06:00
CRDT- 2013/01/29 06:00
PHST- 2012/11/05 00:00 [received]
PHST- 2013/01/14 00:00 [revised]
PHST- 2013/01/14 00:00 [accepted]
PHST- 2013/01/29 06:00 [entrez]
PHST- 2013/01/29 06:00 [pubmed]
PHST- 2014/01/01 06:00 [medline]
AID - 10.1111/dom.12070 [doi]
PST - ppublish
SO  - Diabetes Obes Metab. 2013 Jun;15(6):546-57. doi: 10.1111/dom.12070. Epub 2013 Feb 
      25.