PMID- 23352690
OWN - NLM
STAT- MEDLINE
DCOM- 20140116
LR  - 20220331
IS  - 1471-4973 (Electronic)
IS  - 1471-4892 (Print)
IS  - 1471-4892 (Linking)
VI  - 13
IP  - 2
DP  - 2013 Apr
TI  - Menopause, atherosclerosis, and coronary artery disease.
PG  - 186-91
LID - S1471-4892(13)00009-X [pii]
LID - 10.1016/j.coph.2013.01.005 [doi]
AB  - Women have coronary heart disease (CHD) later than men. This review describes 
      studies of CHD risk factors or outcomes based on studies of premenopausal women 
      followed through the menopause transition, and prospective cohort studies of 
      younger or older women with CHD risk markers or disease outcomes in the context 
      of their menopause history. Major early reports from both types of studies are 
      included in order to put more recent work in context. Most attention has been 
      paid to the Healthy Women Study (HWS), Study of Women's Health across the Nation 
      (SWAN), the Nurses' Health Study (NHS), and the Rancho Bernardo Study (RBS) 
      because they continue to produce recent publications designed to distinguish the 
      effect of age from the effect of menopause. Understanding these differences has 
      important implications for women's cardiovascular health, but remains incomplete. 
      Transition studies have relatively short (<10 years) follow-up and exclude women 
      with surgical menopause. Cohort studies suggest that women with oophorectomy are 
      at greater risk for CHD than intact women, pointing to a greater risk from 
      testosterone deficiency than from estradiol levels.
CI  - Copyright (c) 2013 Elsevier Ltd. All rights reserved.
FAU - Barrett-Connor, Elizabeth
AU  - Barrett-Connor E
AD  - Division of Epidemiology, Department of Family and Preventive Medicine, 
      University of California, San Diego, La Jolla, CA 92093-0607, USA. 
      ebarrettconnor@ucsd.edu
LA  - eng
GR  - AG07181/AG/NIA NIH HHS/United States
GR  - R01 AG007181/AG/NIA NIH HHS/United States
GR  - R01 DK031801/DK/NIDDK NIH HHS/United States
GR  - AG028507/AG/NIA NIH HHS/United States
GR  - R37 AG007181/AG/NIA NIH HHS/United States
GR  - R01 AG028507/AG/NIA NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20130123
PL  - England
TA  - Curr Opin Pharmacol
JT  - Current opinion in pharmacology
JID - 100966133
SB  - IM
MH  - Atherosclerosis/*epidemiology/etiology
MH  - Atrial Fibrillation/epidemiology
MH  - Coronary Artery Disease/*epidemiology/etiology
MH  - Depression/epidemiology
MH  - Humans
MH  - *Menopause
MH  - Sleep Wake Disorders/epidemiology
PMC - PMC3646078
MID - NIHMS435996
COIS- This financial support does not represent a conflict of interest.
EDAT- 2013/01/29 06:00
MHDA- 2014/01/17 06:00
PMCR- 2014/04/01
CRDT- 2013/01/29 06:00
PHST- 2012/11/21 00:00 [received]
PHST- 2013/01/04 00:00 [revised]
PHST- 2013/01/07 00:00 [accepted]
PHST- 2013/01/29 06:00 [entrez]
PHST- 2013/01/29 06:00 [pubmed]
PHST- 2014/01/17 06:00 [medline]
PHST- 2014/04/01 00:00 [pmc-release]
AID - S1471-4892(13)00009-X [pii]
AID - 10.1016/j.coph.2013.01.005 [doi]
PST - ppublish
SO  - Curr Opin Pharmacol. 2013 Apr;13(2):186-91. doi: 10.1016/j.coph.2013.01.005. Epub 
      2013 Jan 23.