PMID- 23353153
OWN - NLM
STAT- MEDLINE
DCOM- 20131230
LR  - 20161125
IS  - 1673-4254 (Print)
IS  - 1673-4254 (Linking)
VI  - 33
IP  - 1
DP  - 2013 Jan
TI  - [Accuracy of correlation function method for evaluating pulsed high intensity 
      focused ultrasound].
PG  - 40-3
AB  - OBJECTIVE: To investigate the accuracy of ultrasound monitoring during pulsed 
      high intensity focused ultrasound (PHIFU) treatment and improve the sensitivity 
      of ultrasound monitoring of tissue necrosis caused by PHIFU treatment. METHODS: 
      Bovine liver ex vivo was dot-exposed with HIFU at the therapeutic doses of 2000 J 
      (group A) and 1440 J (group B). The two groups were further divided into groups 
      A1 (power 100 W, duty cycle 100%, irradiate 20 s) A2 (power 100 W, duty cycle 
      50%, irradiate 40 s), A3 (power 100 W, duty cycle 40%, irradiate 50 s), B1 (power 
      120 W, duty cycle 100%, irradiate 12 s), B2 (power 100 W, duty cycle 50%, 
      irradiate 24 s), and B3 (power 100 W, duty cycle 40%, irradiate 30 s). The gray 
      scale changes in the ultrasonic images after the exposures were observed, and the 
      correlation function of the image was calculated before and after the exposure. 
      The accuracy of evaluations based on the correlation function and gray-scale 
      changes was compared. RESULTS: The correct rate of gray scale-based evaluation of 
      tissue necrosis caused by PHIFU was only 51%, while that by correlation 
      function-based evaluation reached 85%. CONCLUSION: Monitoring of tissue necrosis 
      caused by PHIFU treatment can not rely solely on evaluation of gray-scale change 
      of the ultrasound images, and the correlation function-based evaluation can be 
      more accurate and sensitive for that purpose.
FAU - Zhao, Xin
AU  - Zhao X
AD  - College of Biomedical Engineering of, Chongqing Medical University, Chongqing, 
      China. maybee930@126.com
FAU - Zou, Jianzhong
AU  - Zou J
FAU - Wu, Feng
AU  - Wu F
FAU - Liu, Fang
AU  - Liu F
FAU - Jiao, Jiao
AU  - Jiao J
LA  - chi
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Nan Fang Yi Ke Da Xue Xue Bao
JT  - Nan fang yi ke da xue xue bao = Journal of Southern Medical University
JID - 101266132
SB  - IM
MH  - Animals
MH  - Cattle
MH  - High-Intensity Focused Ultrasound Ablation/*methods
MH  - In Vitro Techniques
MH  - Likelihood Functions
MH  - Liver/*diagnostic imaging
MH  - Ultrasonography
EDAT- 2013/01/29 06:00
MHDA- 2014/01/01 06:00
CRDT- 2013/01/29 06:00
PHST- 2013/01/29 06:00 [entrez]
PHST- 2013/01/29 06:00 [pubmed]
PHST- 2014/01/01 06:00 [medline]
PST - ppublish
SO  - Nan Fang Yi Ke Da Xue Xue Bao. 2013 Jan;33(1):40-3.