PMID- 23355263
OWN - NLM
STAT- MEDLINE
DCOM- 20131115
LR  - 20211021
IS  - 1865-3774 (Electronic)
IS  - 0925-5710 (Linking)
VI  - 97
IP  - 2
DP  - 2013 Feb
TI  - High-dose chemotherapy and autologous stem-cell transplantation in Korean 
      patients with relapsed or refractory Hodgkin lymphoma.
PG  - 256-62
LID - 10.1007/s12185-013-1267-2 [doi]
AB  - High-dose chemotherapy and autologous stem-cell transplantation (HDCT-ASCT) is a 
      standard therapy for patients with relapsed or refractory Hodgkin lymphoma (HL). 
      However, its efficacy in Asian patients has not been well investigated. A 
      retrospective analysis of outcomes in 10 consecutive patients who underwent ASCT 
      for HL in a single Korean centre from August 2005 to September 2010 was 
      conducted. The median age was 34.5 years (range 17-64 years) and seven patients 
      were male. Six patients were of stage III-IV at presentation. B symptoms were 
      present in six patients. International Prognostic Score (IPS) was as follows: IPS 
      = 1 (n = 5), IPS = 2 (n = 1), IPS = 4 (n = 2), and IPS = 5 (n = 2). The analysis 
      included nine patients with relapsed HL and one primary refractory case. Four 
      patients were in second complete response and the others were in partial response 
      after salvage chemotherapy. With a median follow-up duration of 58.0 months, 
      3-year progression-free survival rate and overall survival rate from ASCT were 40 
      and 76 %, respectively. The results suggest that the efficacy of high-dose 
      chemotherapy followed by ASCT in Korean patients with refractory or relapsed HL 
      is comparable to that in Western patients.
FAU - Park, Kwonoh
AU  - Park K
AD  - Department of Oncology, Asan Medical Center, University of Ulsan College of 
      Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 138-736, Korea.
FAU - Yoon, Dok Hyun
AU  - Yoon DH
FAU - Kim, Shin
AU  - Kim S
FAU - Park, Chan-Sik
AU  - Park CS
FAU - Huh, Jooryung
AU  - Huh J
FAU - Lee, Sang-Wook
AU  - Lee SW
FAU - Suh, Cheolwon
AU  - Suh C
LA  - eng
PT  - Journal Article
DEP - 20130126
PL  - Japan
TA  - Int J Hematol
JT  - International journal of hematology
JID - 9111627
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
MH  - Female
MH  - Hematopoietic Stem Cell Mobilization
MH  - *Hematopoietic Stem Cell Transplantation/adverse effects
MH  - Hodgkin Disease/diagnosis/mortality/*therapy
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Neoplasm Staging
MH  - Recurrence
MH  - Remission Induction
MH  - Republic of Korea
MH  - Salvage Therapy
MH  - Transplantation Conditioning
MH  - Transplantation, Autologous
MH  - Treatment Outcome
MH  - Young Adult
EDAT- 2013/01/29 06:00
MHDA- 2013/11/16 06:00
CRDT- 2013/01/29 06:00
PHST- 2012/10/07 00:00 [received]
PHST- 2013/01/15 00:00 [accepted]
PHST- 2012/12/30 00:00 [revised]
PHST- 2013/01/29 06:00 [entrez]
PHST- 2013/01/29 06:00 [pubmed]
PHST- 2013/11/16 06:00 [medline]
AID - 10.1007/s12185-013-1267-2 [doi]
PST - ppublish
SO  - Int J Hematol. 2013 Feb;97(2):256-62. doi: 10.1007/s12185-013-1267-2. Epub 2013 
      Jan 26.