PMID- 23356722
OWN - NLM
STAT- MEDLINE
DCOM- 20141103
LR  - 20191210
IS  - 1463-5224 (Electronic)
IS  - 1463-5216 (Linking)
VI  - 16
IP  - 6
DP  - 2013 Nov
TI  - Intra and inter-user reliability of central corneal thickness measurements 
      obtained in healthy feline eyes using a portable spectral-domain optical 
      coherence tomography device.
PG  - 446-50
LID - 10.1111/vop.12029 [doi]
AB  - OBJECTIVE: To determine the intra and inter-user reliability of central corneal 
      thickness (CCT) measurements obtained using a portable spectral-domain optical 
      coherence tomography (SD-OCT) device in healthy feline eyes. ANIMALS: Twenty 
      clinically normal cats. PROCEDURES: Gentle manual restraint was utilized for 
      proper animal positioning. Central corneal thickness measurements were obtained 
      from both eyes of each animal three times by two operators in succession. A 6 mm, 
      corneal pachymetry protocol was performed using the Optovue(R) iVue SD-OCT system. 
      The CCT was automatically calculated using the pachymetry software generated from 
      eight radial scans, 6 mm in length. The CCT was recorded for each operator and 
      compared statistically for both intra and inter-user reliability. RESULTS: Twenty 
      cats (11 CM, 9 SF) with a mean age of 4.7 years were examined. The mean CCT for 
      all eyes examined was 629.08 +/- 47.05 mum. No significant difference in CCT was 
      found based on the eye examined (OD vs. OS) or age of the animal. However, the 
      CCT of spayed females was significantly higher (42.64 +/- 18.0 mum) as compared to 
      castrated males (P = 0.03). There was no significant difference in CCT 
      measurements between replicates performed by the same operator or between 
      operators. The mean difference in CCT between operators was 0.38 mum. The 
      coefficient of variation for each user and between users was very low (range 
      0.68-1.5%). The intra-class correlation coefficient comparing operators was 
      0.975. CONCLUSIONS: The Optovue(R) iVue SD-OCT device is capable of obtaining CCT 
      measurements with excellent intra and interoperator reliability in healthy feline 
      eyes.
CI  - (c) 2013 American College of Veterinary Ophthalmologists.
FAU - Alario, Anthony F
AU  - Alario AF
AD  - Department of Clinical Sciences, Tufts Cummings School of Veterinary Medicine, 
      North Grafton, MA, 01536, USA.
FAU - Pirie, Christopher G
AU  - Pirie CG
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
DEP - 20130129
PL  - England
TA  - Vet Ophthalmol
JT  - Veterinary ophthalmology
JID - 100887377
SB  - IM
MH  - Animals
MH  - *Cats
MH  - Cornea/*anatomy & histology
MH  - Female
MH  - Male
MH  - Observer Variation
MH  - Tomography, Optical Coherence/instrumentation/methods/*veterinary
OTO - NOTNLM
OT  - central corneal thickness
OT  - feline
OT  - optical coherence tomography
OT  - pachymetry
EDAT- 2013/01/30 06:00
MHDA- 2014/11/05 06:00
CRDT- 2013/01/30 06:00
PHST- 2013/01/30 06:00 [entrez]
PHST- 2013/01/30 06:00 [pubmed]
PHST- 2014/11/05 06:00 [medline]
AID - 10.1111/vop.12029 [doi]
PST - ppublish
SO  - Vet Ophthalmol. 2013 Nov;16(6):446-50. doi: 10.1111/vop.12029. Epub 2013 Jan 29.