PMID- 23357322 OWN - NLM STAT- MEDLINE DCOM- 20131017 LR - 20220331 IS - 1938-2375 (Electronic) IS - 1542-8877 (Linking) VI - 43 IP - 6 Suppl DP - 2012 Nov-Dec TI - Automated detection of the foveal center improves SD-OCT measurements of central retinal thickness. PG - S32-7 LID - 10.3928/15428877-20121001-06 [doi] AB - BACKGROUND AND OBJECTIVE: To investigate the performance of an automated foveal center detection algorithm on spectral-domain optical coherence tomography (SD-OCT). PATIENTS AND METHODS: Fifty normal eyes and 50 eyes with early stage dry age-related macular degeneration (AMD) were analyzed. The actual scan center (SC), automatically detected foveal center (AF), and manually identified foveal center (MF) were compared. RESULTS: The mean of the radial distances was 89 +/- 120 mum from MF to SC and 54 +/- 41 mum from MF to AF for normal eyes and 179 +/- 125 mum from SC to MF and 104 +/- 62 mum from AF to MF for eyes with AMD. The differences were statistically significant (P < .001). CONCLUSION: The automated algorithm designed to detect the foveal center was more accurate in detecting the foveal center than relying on the fixation target of the SD-OCT instrument. CI - Copyright 2012, SLACK Incorporated. FAU - Wang, Fenghua AU - Wang F AD - Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida 33136 , USA. FAU - Gregori, Giovanni AU - Gregori G FAU - Rosenfeld, Philip J AU - Rosenfeld PJ FAU - Lujan, Brandon J AU - Lujan BJ FAU - Durbin, Mary K AU - Durbin MK FAU - Bagherinia, Homayoun AU - Bagherinia H LA - eng GR - P30 EY014801/EY/NEI NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, Non-P.H.S. PL - United States TA - Ophthalmic Surg Lasers Imaging JT - Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye JID - 101155780 SB - IM MH - Algorithms MH - *Fovea Centralis MH - Humans MH - Image Processing, Computer-Assisted/methods MH - Macular Degeneration/*diagnosis MH - Pattern Recognition, Automated/methods MH - Tomography, Optical Coherence/*methods/standards EDAT- 2013/01/30 06:00 MHDA- 2013/10/18 06:00 CRDT- 2013/01/30 06:00 PHST- 2012/04/26 00:00 [received] PHST- 2012/09/27 00:00 [accepted] PHST- 2013/01/30 06:00 [entrez] PHST- 2013/01/30 06:00 [pubmed] PHST- 2013/10/18 06:00 [medline] AID - 10.3928/15428877-20121001-06 [doi] PST - ppublish SO - Ophthalmic Surg Lasers Imaging. 2012 Nov-Dec;43(6 Suppl):S32-7. doi: 10.3928/15428877-20121001-06.