PMID- 23360296 OWN - NLM STAT- MEDLINE DCOM- 20131217 LR - 20211021 IS - 1557-8534 (Electronic) IS - 1547-3287 (Print) IS - 1547-3287 (Linking) VI - 22 IP - 12 DP - 2013 Jun 15 TI - Mammary stem cell research in veterinary science: an update. PG - 1743-51 LID - 10.1089/scd.2012.0677 [doi] AB - The mammary gland is an organ with a remarkable regenerative capacity that can undergo multiple cycles of proliferation, lactation, and involution. Growing evidence suggests that these changes are driven by the coordinated division and differentiation of mammary stem cell populations (MaSC). Whereas information regarding MaSC and their role in comparative mammary gland physiology is readily available in human and mice, such information remains scarce in most veterinary mammal species such as cows, horses, sheep, goats, pigs, and dogs. We believe that a better knowledge on the MaSC in these species will not only help to gain more insights into mammary gland (patho) physiology in veterinary medicine, but will also be of value for human medicine. Therefore, this review summarizes the current knowledge on stem cell isolation and characterization in different mammals of veterinary importance. FAU - Borena, Bizunesh M AU - Borena BM AD - Department of Comparative Physiology and Biometrics, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium. FAU - Bussche, Leen AU - Bussche L FAU - Burvenich, Christian AU - Burvenich C FAU - Duchateau, Luc AU - Duchateau L FAU - Van de Walle, Gerlinde R AU - Van de Walle GR LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review DEP - 20130305 PL - United States TA - Stem Cells Dev JT - Stem cells and development JID - 101197107 RN - 0 (Biomarkers) SB - IM MH - Animals MH - Biomarkers/metabolism MH - Cattle MH - Cell Differentiation MH - Cell Separation/methods MH - Dogs MH - Epithelial Cells/cytology/metabolism MH - Female MH - Goats MH - Horses MH - Mammary Glands, Animal/*cytology/metabolism MH - Mice MH - Neoplastic Stem Cells/metabolism/*pathology MH - Sheep, Domestic MH - *Stem Cell Research MH - Stem Cells/*cytology/metabolism MH - Swine PMC - PMC3668508 EDAT- 2013/01/31 06:00 MHDA- 2013/12/18 06:00 PMCR- 2014/06/15 CRDT- 2013/01/31 06:00 PHST- 2013/01/31 06:00 [entrez] PHST- 2013/01/31 06:00 [pubmed] PHST- 2013/12/18 06:00 [medline] PHST- 2014/06/15 00:00 [pmc-release] AID - 10.1089/scd.2012.0677 [pii] AID - 10.1089/scd.2012.0677 [doi] PST - ppublish SO - Stem Cells Dev. 2013 Jun 15;22(12):1743-51. doi: 10.1089/scd.2012.0677. Epub 2013 Mar 5.