PMID- 23365401
OWN - NLM
STAT- MEDLINE
DCOM- 20130729
LR  - 20220310
IS  - 1525-3163 (Electronic)
IS  - 0021-8812 (Linking)
VI  - 90 Suppl 4
DP  - 2012 Dec
TI  - Effects of a simple or a complex starter microbiota on intestinal microbiota 
      composition in caesarean derived piglets.
PG  - 433-5
LID - 10.2527/jas.53850 [doi]
AB  - The present study was designed to develop a model in piglets that allows the 
      investigation of the effects of postnatal association with a simple or a complex 
      microbiota on gut health and development. Thirty piglets from 2 sows were 
      obtained by caesarean delivery (day 0) and were equally divided over 2 treatment 
      groups housed in separate clean, nonsterile rooms. All piglets received orally a 
      simple microbiota consisting of Lactobacillus amylovorus, Clostridium glycolicum, 
      and Parabacteroides spp. on days 1, 2, and 3 after birth. On day 3 and 4 the 
      piglets received either a complex microbiota by providing them with a fecal 
      inoculant of an adult sow [complex association (CA)] or a placebo inoculant 
      [simple association (SA)]. Fecal microbiota composition, as determined by 
      denaturing gradient gel electrophoresis and by pig intestinal tract chip 
      (PITChip) analysis of 16S rRNA genes (days 3, 5, 7, 14, and 28), was less diverse 
      in the SA group compared to the CA group. A difference in fecal microbiota 
      composition between treatments persisted until the end of the study. It was 
      concluded that the composition of microbiota in feces of cesarean 
      delivery-derived piglets is influenced by bacterial association in the first days 
      after birth. Differences in fecal microbiota composition between piglets exposed 
      to a simple or complex inoculum at early age persisted for at least 3 wk.
FAU - Jansman, A J M
AU  - Jansman AJ
AD  - Wageningen UR Livestock Research, P.O. Box 65, 8200 AB Lelystad, The Netherlands. 
      Alfons.Jansman@wur.nl
FAU - Zhang, J
AU  - Zhang J
FAU - Koopmans, S J
AU  - Koopmans SJ
FAU - Dekker, R A
AU  - Dekker RA
FAU - Smidt, H
AU  - Smidt H
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Anim Sci
JT  - Journal of animal science
JID - 8003002
SB  - IM
MH  - Animal Feed/*analysis
MH  - Animal Nutritional Physiological Phenomena
MH  - Animals
MH  - Bacteroidaceae
MH  - Cesarean Section/*veterinary
MH  - Clostridium
MH  - Diet/veterinary
MH  - Female
MH  - Intestines/*microbiology
MH  - Lactobacillus acidophilus
MH  - Pregnancy
MH  - *Probiotics
MH  - Swine/*growth & development/immunology/*microbiology
EDAT- 2013/02/13 06:00
MHDA- 2013/07/31 06:00
CRDT- 2013/02/01 06:00
PHST- 2013/02/01 06:00 [entrez]
PHST- 2013/02/13 06:00 [pubmed]
PHST- 2013/07/31 06:00 [medline]
AID - 90/Supplement_4/433 [pii]
AID - 10.2527/jas.53850 [doi]
PST - ppublish
SO  - J Anim Sci. 2012 Dec;90 Suppl 4:433-5. doi: 10.2527/jas.53850.