PMID- 23368914
OWN - NLM
STAT- MEDLINE
DCOM- 20130722
LR  - 20130201
IS  - 1532-7914 (Electronic)
IS  - 0163-5581 (Linking)
VI  - 65
IP  - 1
DP  - 2013
TI  - The impact of nutritional status, nutritional risk, and nutritional treatment on 
      clinical outcome of 2248 hospitalized cancer patients: a multi-center, 
      prospective cohort study in Chinese teaching hospitals.
PG  - 62-70
LID - 10.1080/01635581.2013.741752 [doi]
AB  - To better understand the impact of undernutrition, nutritional risk, and 
      nutritional treatment on the clinical outcomes of hospitalized cancer patients in 
      China, the authors conducted a multicenter, cross-sectional study with 2248 
      cancer patients from 20 hospitals from January to June 2010. The authors defined 
      19.7% and 26.8% patients as undernourished at baseline and reassessment, 
      respectively. Patients with gastrointestinal malignancies had a higher rate of 
      undernutrition than other patients. The nutritional risk rate was 24.6% and 40.2% 
      at baseline and reassessment, respectively. For patients with nutritional risk, 
      the relative risk (RR) of adverse events (AEs) significantly increased with and 
      without nutritional treatment. In comparison with the nonnutritional treatment 
      subgroup, patients who received enteral nutrition (EN) or total parenteral 
      nutrition (TPN) significantly reduced the RR of AE development. The RR of AEs for 
      EN and TPN were 0.08 (95% CI: 0.01-0.62) and 0.56 (95% CI: 0.33-0.96), 
      respectively. Separated nutrient infusion increased the risk of AEs. The authors 
      concluded that undernutrition and nutritional risk are general problems that 
      impact the outcomes of hospitalized cancer patients in China. Higher NRS2002 
      scores are related to AE risk but not weight loss. In nutritional treatment, EN 
      and TPN can significantly reduce the risk of AEs.
FAU - Pan, Hongming
AU  - Pan H
AD  - Department of Medical Oncology, Sir Run Run Shaw Hospital, Zhejiang University 
      School of Medicine, Hangzhou, Zhejiang, China. 10518167@zju.edu.cn
FAU - Cai, Sanjun
AU  - Cai S
FAU - Ji, Jiafu
AU  - Ji J
FAU - Jiang, Zhiwei
AU  - Jiang Z
FAU - Liang, Houjie
AU  - Liang H
FAU - Lin, Feng
AU  - Lin F
FAU - Liu, Xiyong
AU  - Liu X
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Nutr Cancer
JT  - Nutrition and cancer
JID - 7905040
SB  - IM
MH  - Adult
MH  - Aged
MH  - China
MH  - Cohort Studies
MH  - Cross-Sectional Studies
MH  - Enteral Nutrition
MH  - Female
MH  - Hospitals, Teaching
MH  - Humans
MH  - Male
MH  - Malnutrition/epidemiology/etiology
MH  - Middle Aged
MH  - Neoplasms/complications/*diet therapy
MH  - *Nutritional Status
MH  - Parenteral Nutrition, Total
MH  - Prospective Studies
MH  - Risk Factors
MH  - Treatment Outcome
EDAT- 2013/02/02 06:00
MHDA- 2013/07/23 06:00
CRDT- 2013/02/02 06:00
PHST- 2013/02/02 06:00 [entrez]
PHST- 2013/02/02 06:00 [pubmed]
PHST- 2013/07/23 06:00 [medline]
AID - 10.1080/01635581.2013.741752 [doi]
PST - ppublish
SO  - Nutr Cancer. 2013;65(1):62-70. doi: 10.1080/01635581.2013.741752.