PMID- 23380649
OWN - NLM
STAT- MEDLINE
DCOM- 20140121
LR  - 20220330
IS  - 1477-0970 (Electronic)
IS  - 1352-4585 (Linking)
VI  - 19
IP  - 7
DP  - 2013 Jun
TI  - Adverse events after endovascular treatment of chronic cerebro-spinal venous 
      insufficiency (CCSVI) in patients with multiple sclerosis.
PG  - 961-3
LID - 10.1177/1352458513475491 [doi]
AB  - Although it is debated whether chronic cerebro-spinal venous insufficiency 
      (CCSVI) plays a role in multiple sclerosis (MS) development, many patients 
      undergo endovascular treatment (ET) of CCSVI. A study is ongoing in Italy to 
      evaluate the clinical outcome of ET. Severe adverse events (AEs) occurred in 
      15/462 subjects at a variable interval after ET: jugular thrombosis in seven 
      patients, tetraventricular hydrocephalus, stroke, paroxysmal atrial fibrillation, 
      status epilepticus, aspiration pneumonia, hypertension with tachicardia, or 
      bleeding of bedsore in the remaining seven cases. One patient died because of 
      myocardial infarction 10 weeks after ET. The risk of severe AEs related to ET for 
      CCSVI must be carefully considered.
FAU - Ghezzi, A
AU  - Ghezzi A
AD  - Centro Studi Sclerosi Multipla, Ospedale di Gallarate, Italy. 
      angelo.ghezzi@aogallarate.it
FAU - Annovazzi, P
AU  - Annovazzi P
FAU - Amato, M P
AU  - Amato MP
FAU - Capello, E
AU  - Capello E
FAU - Cavalla, P
AU  - Cavalla P
FAU - Cocco, E
AU  - Cocco E
FAU - Falcini, M
AU  - Falcini M
FAU - Gallo, A
AU  - Gallo A
FAU - Patti, F
AU  - Patti F
FAU - Perini, P
AU  - Perini P
FAU - Rodegher, M E
AU  - Rodegher ME
FAU - Rovaris, M
AU  - Rovaris M
FAU - Rottoli, M R
AU  - Rottoli MR
FAU - Comi, G
AU  - Comi G
CN  - MS Study Group-Italian Society of Neurology
LA  - eng
PT  - Journal Article
DEP - 20130204
PL  - England
TA  - Mult Scler
JT  - Multiple sclerosis (Houndmills, Basingstoke, England)
JID - 9509185
SB  - IM
EIN - Mult Scler. 2014 May;20(6):768. PMID: 28072565
MH  - Adult
MH  - Brain/blood supply
MH  - Endovascular Procedures/*adverse effects
MH  - Female
MH  - Humans
MH  - Male
MH  - Multiple Sclerosis/etiology/*therapy
MH  - Spinal Cord/blood supply
MH  - Venous Insufficiency/complications/*therapy
OTO - NOTNLM
OT  - CCSVI
OT  - endovascular treatment
OT  - multiple sclerosis
EDAT- 2013/02/06 06:00
MHDA- 2014/01/22 06:00
CRDT- 2013/02/06 06:00
PHST- 2013/02/06 06:00 [entrez]
PHST- 2013/02/06 06:00 [pubmed]
PHST- 2014/01/22 06:00 [medline]
AID - 1352458513475491 [pii]
AID - 10.1177/1352458513475491 [doi]
PST - ppublish
SO  - Mult Scler. 2013 Jun;19(7):961-3. doi: 10.1177/1352458513475491. Epub 2013 Feb 4.