PMID- 23386389
OWN - NLM
STAT- MEDLINE
DCOM- 20140226
LR  - 20190907
IS  - 1348-4540 (Electronic)
IS  - 0918-8959 (Linking)
VI  - 60
IP  - 6
DP  - 2013
TI  - A large functioning parathyroid cyst in a patient with multiple endocrine 
      neoplasia type 1.
PG  - 709-14
AB  - A 62-year-old woman presented with a mass on the left side of the neck. 
      Biochemical testing revealed primary hyperparathyroidism. Further, a prolactinoma 
      was detected, and the patient's son and daughter also had primary 
      hyperparathyroidism, indicating that the patient had multiple endocrine neoplasia 
      type 1 (MEN1). Neck ultrasonography revealed several cystic nodules (</= 30 mm) 
      that appeared to be adenomatous. After parathyroidectomy with 
      autotransplantation, the largest cystic mass, in the left lower thyroid lobe, was 
      pathologically diagnosed as a functioning parathyroid cyst, and all laboratory 
      data returned to normal. On genetic analysis of blood, we found a novel single 
      base insertion (duplication) in exon 10 codon 552 of the MEN1 gene (c1659dupT) 
      that creates an early stop codon. This is the first case report of a parathyroid 
      cyst resulting from parathyroid hyperplasia in a MEN1 patient.
FAU - Tamiya, Hiroyuki
AU  - Tamiya H
AD  - Division of Endocrinology, Toranomon Hospital Endocrine Center, Tokyo 105-8470, 
      Japan. tamiyah-tky@umin.ac.jp
FAU - Miyakawa, Megumi
AU  - Miyakawa M
FAU - Suzuki, Hisanori
AU  - Suzuki H
FAU - Takeshita, Akira
AU  - Takeshita A
FAU - Ohashi, Kenichi
AU  - Ohashi K
FAU - Usui, Takeshi
AU  - Usui T
FAU - Miura, Daishu
AU  - Miura D
FAU - Takeuchi, Yasuhiro
AU  - Takeuchi Y
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20130202
PL  - Japan
TA  - Endocr J
JT  - Endocrine journal
JID - 9313485
SB  - IM
MH  - Adenoma/complications/diagnosis
MH  - Cysts/*complications/diagnosis
MH  - Female
MH  - Humans
MH  - Hyperparathyroidism, Primary/diagnosis/*etiology
MH  - Middle Aged
MH  - Multiple Endocrine Neoplasia Type 1/*complications/diagnosis
MH  - Parathyroid Neoplasms/*complications/diagnosis
MH  - Pituitary Neoplasms/complications/diagnosis
MH  - Prolactinoma/complications/diagnosis
EDAT- 2013/02/07 06:00
MHDA- 2014/02/27 06:00
CRDT- 2013/02/07 06:00
PHST- 2013/02/07 06:00 [entrez]
PHST- 2013/02/07 06:00 [pubmed]
PHST- 2014/02/27 06:00 [medline]
AID - DN/JST.JSTAGE/endocrj/EJ12-0306 [pii]
AID - 10.1507/endocrj.ej12-0306 [doi]
PST - ppublish
SO  - Endocr J. 2013;60(6):709-14. doi: 10.1507/endocrj.ej12-0306. Epub 2013 Feb 2.