PMID- 23391990
OWN - NLM
STAT- MEDLINE
DCOM- 20130930
LR  - 20130409
IS  - 1878-7568 (Electronic)
IS  - 1742-7061 (Linking)
VI  - 9
IP  - 5
DP  - 2013 May
TI  - Biocompatibility of printed paper-based arrays for 2-D cell cultures.
PG  - 6704-10
LID - S1742-7061(13)00048-2 [pii]
LID - 10.1016/j.actbio.2013.01.033 [doi]
AB  - The use of paper-based test platforms in cell culture experiments is 
      demonstrated. The arrays used for two-dimensional cell cultures were prepared by 
      printing patterned structures on a paper substrate using a hydrophobic 
      polydimethylsiloxane (PDMS) ink. The non-printed, PDMS-free areas formed the 
      array for the cell growth experiments. Cell imaging was enabled by using a 
      lipophilic staining agent. A set of coated paper substrates was prepared to study 
      the effect of the physicochemical properties of the substrate (topography, 
      roughness and surface energetics) on cell attachment and growth. The studied 
      paper substrates were found to be cell-repellent or cell-supporting. Cell growth 
      was supported by substrates with a large bearing area, low surface area ratio 
      (Sdr), high total surface free energy and an intermediate electron donor surface 
      energy component. The cells were grown to full confluency within 72 h.
CI  - Copyright (c) 2013 Acta Materialia Inc. Published by Elsevier Ltd. All rights 
      reserved.
FAU - Juvonen, Helka
AU  - Juvonen H
AD  - Center of Excellence for Functional Materials, Laboratory of Physical Chemistry, 
      Abo Akademi University, Turku, Finland. helka.juvonen@abo.fi
FAU - Maattanen, Anni
AU  - Maattanen A
FAU - Lauren, Patrick
AU  - Lauren P
FAU - Ihalainen, Petri
AU  - Ihalainen P
FAU - Urtti, Arto
AU  - Urtti A
FAU - Yliperttula, Marjo
AU  - Yliperttula M
FAU - Peltonen, Jouko
AU  - Peltonen J
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130204
PL  - England
TA  - Acta Biomater
JT  - Acta biomaterialia
JID - 101233144
RN  - 0 (Biocompatible Materials)
SB  - IM
MH  - *Biocompatible Materials
MH  - Cell Adhesion
MH  - Cell Culture Techniques
MH  - Cell Division
MH  - Cell Line
MH  - Microscopy, Atomic Force
MH  - Microscopy, Fluorescence
MH  - *Paper
EDAT- 2013/02/09 06:00
MHDA- 2013/10/01 06:00
CRDT- 2013/02/09 06:00
PHST- 2012/08/29 00:00 [received]
PHST- 2012/11/26 00:00 [revised]
PHST- 2013/01/28 00:00 [accepted]
PHST- 2013/02/09 06:00 [entrez]
PHST- 2013/02/09 06:00 [pubmed]
PHST- 2013/10/01 06:00 [medline]
AID - S1742-7061(13)00048-2 [pii]
AID - 10.1016/j.actbio.2013.01.033 [doi]
PST - ppublish
SO  - Acta Biomater. 2013 May;9(5):6704-10. doi: 10.1016/j.actbio.2013.01.033. Epub 
      2013 Feb 4.