PMID- 23399845
OWN - NLM
STAT- MEDLINE
DCOM- 20130830
LR  - 20151119
IS  - 1932-751X (Electronic)
IS  - 1932-7501 (Linking)
VI  - 33
IP  - 2
DP  - 2013 Mar-Apr
TI  - Comprehensive pulmonary rehabilitation results in clinically meaningful 
      improvements in anxiety and depression in patients with chronic obstructive 
      pulmonary disease.
PG  - 123-7
LID - 10.1097/HCR.0b013e31828254d4 [doi]
AB  - PURPOSE: Pulmonary rehabilitation (PR) improves anxiety and depression in 
      patients with chronic obstructive pulmonary disease. However, little is known 
      regarding its ability to produce clinically meaningful improvements in these 
      outcomes. METHODS: We retrospectively analyzed 366 patients who participated in 
      our 8-week outpatient PR program. The Hospital Anxiety and Depression Scale was 
      used to screen for anxiety and depression symptoms (HADA and HADD, respectively); 
      for both, a score of >/= 10 was considered abnormal, and a change of 1.5 units or 
      greater in magnitude was considered the threshold for a minimal clinically 
      important difference (MCID). Other outcomes included the Chronic Respiratory 
      Disease Questionnaire and the 6-Minute Walk Test. RESULTS: Of the 366 patients, 
      257 (70%) completed the program and 235 (64%) completed final outcome evaluation. 
      At program entry, 25% had abnormal anxiety scores and 17% had abnormal depression 
      scores; these dropped to 9% and 6%, respectively, in those patients completing 
      outcome analyses (P < .0001). Abnormal HADA and HADD scores predicted 
      noncompletion of the program. Among patients who completed PR, there were 
      significant improvements on all dimensions (increased walk distance, increased 
      quality of life, and reduced symptoms of depression and anxiety). Of the total 
      group, the MCID was exceeded in 41% and 46% for HADA and HADD, respectively. Of 
      those with abnormal anxiety scores at baseline who completed outcome analysis (n 
      = 44), 91% surpassed the MCID, while of those with abnormal depression scores at 
      entry (n = 30), 93% surpassed the MCID. CONCLUSIONS: Pulmonary rehabilitation 
      results in substantial and clinically meaningful changes in both anxiety and 
      depression.
FAU - Bhandari, Neha Jain
AU  - Bhandari NJ
AD  - University of Connecticut Health Center, Farmington, CT, USA. 
      nejain_1984@yahoo.com
FAU - Jain, Tarun
AU  - Jain T
FAU - Marolda, Corliss
AU  - Marolda C
FAU - ZuWallack, Richard L
AU  - ZuWallack RL
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Cardiopulm Rehabil Prev
JT  - Journal of cardiopulmonary rehabilitation and prevention
JID - 101291247
SB  - IM
MH  - Aged
MH  - Anxiety/diagnosis/*epidemiology
MH  - Depression/diagnosis/*epidemiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Psychiatric Status Rating Scales
MH  - Pulmonary Disease, Chronic Obstructive/psychology/*rehabilitation
MH  - *Quality of Life
MH  - Retrospective Studies
MH  - Severity of Illness Index
MH  - Surveys and Questionnaires
MH  - Treatment Outcome
EDAT- 2013/02/13 06:00
MHDA- 2013/08/31 06:00
CRDT- 2013/02/13 06:00
PHST- 2013/02/13 06:00 [entrez]
PHST- 2013/02/13 06:00 [pubmed]
PHST- 2013/08/31 06:00 [medline]
AID - 10.1097/HCR.0b013e31828254d4 [doi]
PST - ppublish
SO  - J Cardiopulm Rehabil Prev. 2013 Mar-Apr;33(2):123-7. doi: 
      10.1097/HCR.0b013e31828254d4.