PMID- 23410121
OWN - NLM
STAT- MEDLINE
DCOM- 20131209
LR  - 20191210
IS  - 1944-0057 (Electronic)
IS  - 1944-0057 (Linking)
VI  - 30
IP  - 4
DP  - 2013
TI  - Simultaneous determination of pyrimethanil, cyprodinil, mepanipyrim and its 
      metabolite in fresh and home-processed fruit and vegetables by a QuEChERS method 
      coupled with UPLC-MS/MS.
PG  - 713-21
LID - 10.1080/19440049.2013.768777 [doi]
AB  - A QuEChERS procedure for the simultaneous determination of pyrimethanil, 
      cyprodinil, mepanipyrim and its metabolite (M31) in fresh and processed fruit and 
      vegetables was developed using ultra-performance liquid chromatography/tandem 
      mass spectrometry (UPLC-MS/MS). The determination of the four target compounds 
      was achieved in less than 6.0 min using an electrospray ionisation source in 
      positive mode. The limits of detection (LODs) were below 0.4 mug kg(-)(1), while the 
      limits of quantification (LOQs) did not exceed 1.5 mug kg(-)(1) for all studied 
      matrices. Good linearity of the calibration curves was obtained over the range 
      from 0.002 to 2 mg kg(-)(1), with correlation coefficients higher than 0.999. The 
      average recoveries of this method in apple, peach, cabbage and tomato at the five 
      spiked levels (0.002, 0.01, 0.05, 0.20 and 2.0 mg kg(-)(1)) ranged from 81.5% to 
      107.3% with relative standard deviations (RSDs) in the range of 1.5-13.9% (n = 5) 
      for all analytes. Residue levels of anilinopyrimidine fungicides in fresh and 
      home-processed apple, peach, cabbage and tomato were also studied. The results 
      indicate that residue levels are significantly reduced following washing, peeling 
      and boiling, and there is no toxic metabolite of mepanipyrim (M31) which is 
      detected during boiling. This study provides a theoretical basis for China to 
      draw up maximum residue limits (MRLs) and protect consumers from the negative 
      health effects of pesticide residues detected in fruit and vegetables.
FAU - Liang, Xuyang
AU  - Liang X
AD  - State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of 
      Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, 
      China.
FAU - Liu, Xingang
AU  - Liu X
FAU - Dong, Fengshou
AU  - Dong F
FAU - Xu, Jun
AU  - Xu J
FAU - Qin, Dongmei
AU  - Qin D
FAU - Li, Yuanbo
AU  - Li Y
FAU - Tian, Yingying
AU  - Tian Y
FAU - Zhang, Ying
AU  - Zhang Y
FAU - Han, Yongtao
AU  - Han Y
FAU - Zheng, Yongquan
AU  - Zheng Y
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Validation Study
DEP - 20130214
PL  - England
TA  - Food Addit Contam Part A Chem Anal Control Expo Risk Assess
JT  - Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & 
      risk assessment
JID - 101485040
RN  - 0 (Pyrimidines)
RN  - 42P6T6OFWZ (cyprodinil)
RN  - 6IA5HP6C8Z (pyrimethanil)
RN  - B150X76OJY (mepanipyrim)
SB  - IM
MH  - Calibration
MH  - Chromatography, Liquid/*methods
MH  - Fruit/*chemistry
MH  - Limit of Detection
MH  - Pyrimidines/*analysis
MH  - Reproducibility of Results
MH  - Tandem Mass Spectrometry/*methods
MH  - Vegetables/*chemistry
EDAT- 2013/02/16 06:00
MHDA- 2013/12/16 06:00
CRDT- 2013/02/16 06:00
PHST- 2013/02/16 06:00 [entrez]
PHST- 2013/02/16 06:00 [pubmed]
PHST- 2013/12/16 06:00 [medline]
AID - 10.1080/19440049.2013.768777 [doi]
PST - ppublish
SO  - Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2013;30(4):713-21. 
      doi: 10.1080/19440049.2013.768777. Epub 2013 Feb 14.