PMID- 23419586
OWN - NLM
STAT- MEDLINE
DCOM- 20140408
LR  - 20220330
IS  - 1618-131X (Electronic)
IS  - 1438-4639 (Linking)
VI  - 216
IP  - 6
DP  - 2013 Nov
TI  - Body burden monitoring of dioxins and other organic substances in workers at a 
      hazardous waste incinerator.
PG  - 728-34
LID - S1438-4639(13)00012-6 [pii]
LID - 10.1016/j.ijheh.2013.01.003 [doi]
AB  - The construction in Constanti (Tarragona County, Catalonia) of the first, and up 
      till now the only hazardous waste incinerator (HWI) in Spain, finished in 1999. 
      In this study, we measured the concentrations of a number of organic substances 
      determined in blood and urine of the HWI workers. Samples of 18 men and 9 women, 
      classified according to their respective workplaces, were collected in 2011, 
      after approximately 12 years of regular operations in the facility. The current 
      results were compared with those of the baseline survey, as well as with the most 
      recent surveys performed in 2008, 2009 and 2010. Plasma analyses were carried out 
      for hexachlorobenzene (HCB), polychlorinated biphenyls (PCBs 28, 52, 101, 138, 
      153, and 180) and polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs), 
      while the levels of 2,4- and 2,5-dichlorophenol (DCP), 2,4,5- and 
      2,4,6-trichlorophenol (TCP), pentachlorophenol (PCP) and 1-hydroxypyrene (1-HP) 
      were measured in urine samples. In plasma, the mean concentrations were the 
      following: 10.8mug/kg lipid for HCB; 0.8mug/kg lipid for PCB28; 0.3mug/kg lipid for 
      PCB52; 0.5mug/kg lipid for PCB101; 42.2mug/kg lipid for PCB138; 18.5mug/kg lipid for 
      PCB153, and 51.2mug/kg lipid for PCB180. For PCDD/Fs, the mean concentration was 
      4.6ng I-TEQ/kg lipid (4.7ng WHO-TEQ/kg lipid). These levels, as well as those 
      found in urine samples, are in agreement with the data of previous surveys 
      performed in the same area. The current results in HWI workers do not show any 
      evident sign of occupational exposure to PCDD/Fs and other organic substances. 
      However, these results must be considered only as an indication of potential 
      exposure, as the study presents notable limitations, such as the reduced number 
      of participants and the lack of data relative to the air concentrations of 
      chemicals. Consequently, general conclusions cannot be derived and the results 
      should not be used as a basis for the implementation of industrial hygiene 
      measures in other HWIs.
CI  - Copyright (c) 2013 Elsevier GmbH. All rights reserved.
FAU - Mari, Montse
AU  - Mari M
AD  - Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, 
      Universitat Rovira i Virgili, Sant Llorenc 21, 43201 Reus, Catalonia, Spain; 
      Environmental Engineering Laboratory, Departament d'Enginyeria Quimica, 
      Universitat Rovira i Virgili, Av. Paisos Catalans 26, 43007 Tarragona, Catalonia, 
      Spain.
FAU - Nadal, Marti
AU  - Nadal M
FAU - Schuhmacher, Marta
AU  - Schuhmacher M
FAU - Domingo, Jose L
AU  - Domingo JL
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130216
PL  - Germany
TA  - Int J Hyg Environ Health
JT  - International journal of hygiene and environmental health
JID - 100898843
RN  - 0 (Benzene Derivatives)
RN  - 0 (Benzofurans)
RN  - 0 (Chlorophenols)
RN  - 0 (Dioxins)
RN  - 0 (Environmental Pollutants)
RN  - 0 (Hazardous Waste)
RN  - 0 (Pyrenes)
RN  - 3B11G9AKBA (2,5-dichlorophenol)
RN  - 4Z87H0LKUY (Hexachlorobenzene)
RN  - 8U54U639VI (dibenzofuran)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
RN  - MHS8C5BAUZ (2,4,6-trichlorophenol)
RN  - N2H6O5V707 (1-hydroxypyrene)
SB  - IM
MH  - Benzene Derivatives/*blood/urine
MH  - Benzofurans/blood
MH  - Body Burden
MH  - Chlorophenols/urine
MH  - Dioxins/*blood
MH  - Environmental Monitoring
MH  - Environmental Pollutants/*metabolism
MH  - Female
MH  - *Hazardous Waste
MH  - Hexachlorobenzene/blood
MH  - Humans
MH  - Incineration
MH  - Male
MH  - Occupational Exposure/*analysis
MH  - Polychlorinated Biphenyls/blood
MH  - Pyrenes/*urine
MH  - *Refuse Disposal
MH  - Spain
OTO - NOTNLM
OT  - Hazardous waste incinerator (HWI)
OT  - Organic substances
OT  - Plasma
OT  - Urine
OT  - Workers
EDAT- 2013/02/20 06:00
MHDA- 2014/04/09 06:00
CRDT- 2013/02/20 06:00
PHST- 2012/07/11 00:00 [received]
PHST- 2013/01/04 00:00 [revised]
PHST- 2013/01/23 00:00 [accepted]
PHST- 2013/02/20 06:00 [entrez]
PHST- 2013/02/20 06:00 [pubmed]
PHST- 2014/04/09 06:00 [medline]
AID - S1438-4639(13)00012-6 [pii]
AID - 10.1016/j.ijheh.2013.01.003 [doi]
PST - ppublish
SO  - Int J Hyg Environ Health. 2013 Nov;216(6):728-34. doi: 
      10.1016/j.ijheh.2013.01.003. Epub 2013 Feb 16.