PMID- 23423163
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20130221
LR  - 20211021
IS  - 2233-601X (Print)
IS  - 2093-6516 (Electronic)
IS  - 2233-601X (Linking)
VI  - 46
IP  - 1
DP  - 2013 Feb
TI  - Clinical outcomes of thromboendarterectomy for chronic thromboembolic pulmonary 
      hypertension: 12-year experience.
PG  - 41-8
LID - 10.5090/kjtcs.2013.46.1.41 [doi]
AB  - BACKGROUND: We present our 12-year experience of pulmonary thromboendarterectomy 
      in patients with chronic thromboembolic pulmonary hypertension. MATERIALS AND 
      METHODS: Between January 1999 and March 2011, 16 patients underwent pulmonary 
      thromboendarterectomy. Eleven patients (69%) were classified as functional class 
      III or IV based on the New York Heart Association (NYHA) classification. Seven 
      patients had a history of inferior vena cava filter insertion, and 5 patients 
      showed coagulation disorders. Pulmonary thromboendarterectomy was performed 
      during total circulatory arrest with deep hypothermia in 14 patients. RESULTS: 
      In-hospital mortality and late death occurred in 2 patients (12.5%) and 1 patient 
      (6.3%), respectively. Extracorporeal membrane oxygenation support was required in 
      4 patients who developed severe hypoxemia after surgery. Thirteen of the 14 
      survivors have been followed up for 54 months (range, 2 to 141 months). The 
      pulmonary arterial systolic pressure and cardiothoracic ratio on chest 
      radiography was significantly decreased after surgery (76+/-26 mmHg vs. 41+/-17 mmHg, 
      p=0.001; 55%+/-8% vs. 48%+/-3%, p=0.003). Tricuspid regurgitation was reduced from 
      2.1+/-1.1 to 0.7+/-0.6 (p=0.007), and the NYHA functional class was also improved to 
      I or II in 13 patients (81%). These symptomatic and hemodynamic improvements 
      maintained during the late follow-up period. CONCLUSION: Pulmonary 
      thromboendarterectomy for chronic thromboembolic pulmonary hypertension shows 
      good clinical outcomes with acceptable early and long term mortality.
FAU - Oh, Se Jin
AU  - Oh SJ
AD  - Department of Thoracic and Cardiovascular Surgery, Seoul National University 
      Hospital, Seoul National University College of Medicine, Korea.
FAU - Bok, Jin San
AU  - Bok JS
FAU - Hwang, Ho Young
AU  - Hwang HY
FAU - Kim, Kyung-Hwan
AU  - Kim KH
FAU - Kim, Ki Bong
AU  - Kim KB
FAU - Ahn, Hyuk
AU  - Ahn H
LA  - eng
PT  - Journal Article
DEP - 20130206
PL  - Korea (South)
TA  - Korean J Thorac Cardiovasc Surg
JT  - The Korean journal of thoracic and cardiovascular surgery
JID - 101563922
PMC - PMC3573164
OTO - NOTNLM
OT  - Endarterectomy
OT  - Pulmonary arteries
OT  - Thromboembolism
OT  - Tricuspid valve
COIS- No potential conflict of interest relevant to this article was reported.
EDAT- 2013/02/21 06:00
MHDA- 2013/02/21 06:01
PMCR- 2013/02/01
CRDT- 2013/02/21 06:00
PHST- 2012/12/18 00:00 [received]
PHST- 2012/12/31 00:00 [revised]
PHST- 2013/01/02 00:00 [accepted]
PHST- 2013/02/21 06:00 [entrez]
PHST- 2013/02/21 06:00 [pubmed]
PHST- 2013/02/21 06:01 [medline]
PHST- 2013/02/01 00:00 [pmc-release]
AID - 10.5090/kjtcs.2013.46.1.41 [doi]
PST - ppublish
SO  - Korean J Thorac Cardiovasc Surg. 2013 Feb;46(1):41-8. doi: 
      10.5090/kjtcs.2013.46.1.41. Epub 2013 Feb 6.