PMID- 23425009
OWN - NLM
STAT- MEDLINE
DCOM- 20130815
LR  - 20181202
IS  - 1748-295X (Electronic)
IS  - 1748-2941 (Linking)
VI  - 15
IP  - 1
DP  - 2013 Mar
TI  - Cardiac magnetic resonance detection of left ventricular thrombus in acute 
      myocardial infarction.
PG  - 11-6
LID - 10.3109/17482941.2012.741248 [doi]
AB  - INTRODUCTION: Left ventricular thrombosis (LVT) is a possible complication of 
      acute myocardial infarction. Aim of our study was to evaluate incidence and 
      clinical characteristics of patients with LVT after ST elevation myocardial 
      infarction (STEMI) using contrast- enhanced magnetic resonance (CMR). METHODS AND 
      RESULTS: In a prospective cohort of 36 consecutive patients with STEMI acutely 
      reperfused with primary percutaneous coronary intervention, CMR was performed 
      within one week. LVT was found in 7 patients (19%), and was located in left 
      ventricle apex or adherent to antero-septum. Compared to the rest of population 
      patients with LVT have lower ejection fraction (38 +/- 7% versus 51 +/- 6%, P = 
      0.009), larger left ventricle end systolic volume (95.8 +/- 19 ml versus 68.9 +/- 19 
      ml, P = 0.02), higher time to reperfusion (9.3 +/- 7.2 versus 5 +/- 3.6, P = 0.03) 
      and left anterior descending artery was constantly involved (100% versus 41 %, P 
      = 0.06). In 5 cases the LVT was also detected by echocardiography, however, in 2 
      cases it was missed. CONCLUSIONS: The incidence of LVT after STEMI is not 
      negligible and was accurately detected by CMR. Localization of myocardial 
      infarction, time to reperfusion, ejection fraction and left ventricle end 
      systolic volume are the most important predictors of left ventricle thrombus 
      formation.
FAU - Lanzillo, Chiara
AU  - Lanzillo C
AD  - Cardiology Department, Policlinico Casilino, Rome, Italy. 
      chiaralanzilllo@hotmail.com
FAU - Di Roma, Mauro
AU  - Di Roma M
FAU - Sciahbasi, Alessandro
AU  - Sciahbasi A
FAU - Minati, Monia
AU  - Minati M
FAU - Maresca, Luciano
AU  - Maresca L
FAU - Pendenza, Gianluca
AU  - Pendenza G
FAU - Romagnoli, Enrico
AU  - Romagnoli E
FAU - Summaria, Francesco
AU  - Summaria F
FAU - Patrizi, Roberto
AU  - Patrizi R
FAU - Di Luozzo, Marco
AU  - Di Luozzo M
FAU - Preziosi, Paolo
AU  - Preziosi P
FAU - Lioy, Ernesto
AU  - Lioy E
FAU - Romeo, Francesco
AU  - Romeo F
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - England
TA  - Acute Card Care
JT  - Acute cardiac care
JID - 101276603
RN  - 0 (Anticoagulants)
RN  - 0 (Platelet Aggregation Inhibitors)
RN  - 5Q7ZVV76EI (Warfarin)
RN  - A74586SNO7 (Clopidogrel)
RN  - OM90ZUW7M1 (Ticlopidine)
RN  - R16CO5Y76E (Aspirin)
SB  - IM
MH  - Aged
MH  - Anticoagulants/therapeutic use
MH  - Aspirin/therapeutic use
MH  - Clopidogrel
MH  - Cohort Studies
MH  - Drug Therapy, Combination
MH  - Echocardiography
MH  - Female
MH  - Humans
MH  - Incidence
MH  - *Magnetic Resonance Imaging, Cine
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/complications/*diagnosis/therapy
MH  - Percutaneous Coronary Intervention
MH  - Platelet Aggregation Inhibitors/therapeutic use
MH  - Prospective Studies
MH  - Stroke Volume
MH  - Thrombosis/*diagnosis/drug therapy/etiology
MH  - Ticlopidine/analogs & derivatives/therapeutic use
MH  - Ventricular Dysfunction, Left/*diagnosis/etiology/therapy
MH  - Warfarin/therapeutic use
EDAT- 2013/02/22 06:00
MHDA- 2013/08/16 06:00
CRDT- 2013/02/22 06:00
PHST- 2013/02/22 06:00 [entrez]
PHST- 2013/02/22 06:00 [pubmed]
PHST- 2013/08/16 06:00 [medline]
AID - 10.3109/17482941.2012.741248 [doi]
PST - ppublish
SO  - Acute Card Care. 2013 Mar;15(1):11-6. doi: 10.3109/17482941.2012.741248.