PMID- 23434842
OWN - NLM
STAT- MEDLINE
DCOM- 20130827
LR  - 20130307
IS  - 1879-2057 (Electronic)
IS  - 0001-4575 (Linking)
VI  - 53
DP  - 2013 Apr
TI  - Alcohol- or drug-use disorders and motor vehicle accident mortality: a 
      retrospective cohort study.
PG  - 149-55
LID - S0001-4575(13)00021-3 [pii]
LID - 10.1016/j.aap.2013.01.008 [doi]
AB  - A large body of research has linked alcohol consumption and motor vehicle 
      accidents (MVAs), but far fewer studies have estimated the risk of MVA fatality 
      among drug users. Our study addresses this gap. We identified cohorts of 
      individuals hospitalized in California from 1990 to 2005 with ICD-9 diagnoses of 
      methamphetamine- (n=74,170), alcohol- (n=592,406), opioids- (n=68,066), cannabis- 
      (n=47,048), cocaine- (n=48,949), or polydrug-related disorders (n=411,175), and 
      these groups were followed for up to 16 years. Age-, sex-, and race-adjusted 
      standardized mortality rates (SMRs) for deaths due to MVAs were generated in 
      relation to the California general population. Standardized MVA mortality ratios 
      were elevated across all drug cohorts: alcohol (4.5, 95% CI, 4.1-4.9), cocaine 
      (3.8, 95% CI, 2.3-5.3), opioids (2.8, 95% CI, 2.1-3.5), methamphetamine (2.6, 95% 
      CI, 2-3.1), cannabis (2.3, 95% CI, 1.5-3.2) and polydrug (2.6, 95% CI, 2.4-2.9). 
      Males and females had similar MVA SMRs. Our large, population-based study found 
      elevated risk of MVA mortality across all cohorts of individuals with alcohol- or 
      drug-use disorders. Given that illicit drug users are often unaware of or 
      misperceive the impacts of drug use on safe driving, it may be important for 
      health-service or public-health interventions to address such biases and improve 
      road safety.
CI  - Copyright (c) 2013 Elsevier Ltd. All rights reserved.
FAU - Callaghan, Russell C
AU  - Callaghan RC
AD  - Northern Medical Program, University of Northern British Columbia, 3333 
      University Way, Prince George, British Columbia, Canada. Russ.Callaghan@UNBC.ca
FAU - Gatley, Jodi M
AU  - Gatley JM
FAU - Veldhuizen, Scott
AU  - Veldhuizen S
FAU - Lev-Ran, Shaul
AU  - Lev-Ran S
FAU - Mann, Robert
AU  - Mann R
FAU - Asbridge, Mark
AU  - Asbridge M
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130201
PL  - England
TA  - Accid Anal Prev
JT  - Accident; analysis and prevention
JID - 1254476
SB  - IM
MH  - Accidents, Traffic/*mortality
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Alcohol-Related Disorders
MH  - California/epidemiology
MH  - Death Certificates
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Patient Admission/statistics & numerical data
MH  - Retrospective Studies
MH  - Risk Factors
MH  - *Substance-Related Disorders
MH  - Young Adult
EDAT- 2013/02/26 06:00
MHDA- 2013/08/28 06:00
CRDT- 2013/02/26 06:00
PHST- 2012/09/05 00:00 [received]
PHST- 2012/12/03 00:00 [revised]
PHST- 2013/01/17 00:00 [accepted]
PHST- 2013/02/26 06:00 [entrez]
PHST- 2013/02/26 06:00 [pubmed]
PHST- 2013/08/28 06:00 [medline]
AID - S0001-4575(13)00021-3 [pii]
AID - 10.1016/j.aap.2013.01.008 [doi]
PST - ppublish
SO  - Accid Anal Prev. 2013 Apr;53:149-55. doi: 10.1016/j.aap.2013.01.008. Epub 2013 
      Feb 1.