PMID- 23435788
OWN - NLM
STAT- MEDLINE
DCOM- 20140220
LR  - 20211021
IS  - 1432-1971 (Electronic)
IS  - 0172-0643 (Linking)
VI  - 34
IP  - 5
DP  - 2013 Jun
TI  - Porcine bioprosthetic valve in the pulmonary position: mid-term results in the 
      right ventricular outflow tract reconstruction.
PG  - 1190-3
LID - 10.1007/s00246-012-0602-3 [doi]
AB  - Pulmonary valve replacement (PVR) for pulmonary valve insufficiency (PVI) 
      currently represents the most frequent reoperation performed for adults with 
      congenital heart disease. A variety of pulmonary valve substitutes have been 
      used, but none has proved to be ideal. This report reviews the authors' 
      experience using a porcine prosthetic valve in the pulmonary position. Between 
      January 2001 and December 2011, 76 patients (mean age, 36 years; range, 18-64 
      years) underwent PVR for chronic PVI using a porcine bioprosthesis. All the 
      patients had previously undergone surgery: 65 for repair of tetralogy of Fallot 
      and 11 for pulmonary surgical valvotomy. Magnetic resonance imaging (MRI) 
      evaluations before surgery and at the 1-year postoperative follow-up evaluation 
      were compared. Aside from the PVR, 59 patients (59/65, 78 %) received 94 
      associated cardiac surgical procedures. Two hospital deaths occurred. The mean 
      hospital stay was 13 days (range, 7-48 days). At the 1-year control MRI, 
      pulmonary regurgitation fraction, right ventricular end diastolic volume (RVEDV), 
      and RV/LV EDV had improved significantly. During a mean follow-up period of 52 
      months (range, 6-132 months), one patient died. All the patients were categorized 
      as New York heart association (NYHA) functional class 1. No episodes of 
      structural valve deterioration, endocarditis, or thromboembolic event were noted. 
      Echocardiography showed trivial or no PVI in all the patients. The porcine 
      bioprosthetic valves demonstrated excellent midterm results in the RV outflow 
      tract reconstruction. The hemodynamic characteristics of this valve are 
      comparable with those of homografts or valved conduits. It is easy to implant and 
      allows for avoiding extensive dissection, especially of the pulmonary arteries.
FAU - Giamberti, Alessandro
AU  - Giamberti A
AD  - Department of Cardiac Surgery and GUCH Unit, IRCCS Policlinico San Donato, Via 
      Morandi 30, 20097 San Donato M.se, MI, Italy. alegia@hotmail.com
FAU - Chessa, Massimo
AU  - Chessa M
FAU - Reali, Matteo
AU  - Reali M
FAU - Varrica, Alessandro
AU  - Varrica A
FAU - Nuri, Halkawt
AU  - Nuri H
FAU - Isgro, Giuseppe
AU  - Isgro G
FAU - Frigiola, Alessandro
AU  - Frigiola A
FAU - Ranucci, Marco
AU  - Ranucci M
LA  - eng
PT  - Journal Article
DEP - 20130224
PL  - United States
TA  - Pediatr Cardiol
JT  - Pediatric cardiology
JID - 8003849
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Animals
MH  - Female
MH  - *Heart Valve Prosthesis
MH  - Heart Ventricles/abnormalities/*surgery
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Middle Aged
MH  - Pulmonary Valve/abnormalities/*surgery
MH  - Stents
MH  - Swine
MH  - Tetralogy of Fallot/*surgery
MH  - Treatment Outcome
MH  - Ventricular Outflow Obstruction/congenital/*surgery
EDAT- 2013/02/26 06:00
MHDA- 2014/02/22 06:00
CRDT- 2013/02/26 06:00
PHST- 2012/08/14 00:00 [received]
PHST- 2012/11/29 00:00 [accepted]
PHST- 2013/02/26 06:00 [entrez]
PHST- 2013/02/26 06:00 [pubmed]
PHST- 2014/02/22 06:00 [medline]
AID - 10.1007/s00246-012-0602-3 [doi]
PST - ppublish
SO  - Pediatr Cardiol. 2013 Jun;34(5):1190-3. doi: 10.1007/s00246-012-0602-3. Epub 2013 
      Feb 24.