PMID- 23438165
OWN - NLM
STAT- MEDLINE
DCOM- 20140130
LR  - 20221207
IS  - 1440-1819 (Electronic)
IS  - 1323-1316 (Linking)
VI  - 67
IP  - 2
DP  - 2013 Feb
TI  - Association of the BDNF C270T polymorphism with schizophrenia: updated 
      meta-analysis.
PG  - 123-5
LID - 10.1111/pcn.12018 [doi]
AB  - Brain-derived neurotrophic factor (BDNF) has been suggested to play a role in the 
      pathophysiology of schizophrenia. The C270T polymorphism (rs56164415) in the BDNF 
      5'-non-coding region has been extensively investigated for an association with 
      schizophrenia, but with conflicting results. An updated meta-analysis was 
      therefore performed of 13 case-control association studies (3505 patients and 
      3992 controls). An association was found between the T allele and schizophrenia. 
      The association was significant in the East Asian population, but not in the 
      Caucasian population. It is suggested that the BDNF C270T polymorphism 
      contributes to schizophrenia susceptibility, especially in East Asian subjects.
CI  - (c) 2013 The Authors. Psychiatry and Clinical Neurosciences (c) 2013 Japanese Society 
      of Psychiatry and Neurology.
FAU - Watanabe, Yuichiro
AU  - Watanabe Y
AD  - Department of Psychiatry, Niigata University Graduate School of Medical and 
      Dental Sciences, Niigata, Japan. yuichiro@med.niigata-u.ac.jp
FAU - Nunokawa, Ayako
AU  - Nunokawa A
FAU - Someya, Toshiyuki
AU  - Someya T
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PL  - Australia
TA  - Psychiatry Clin Neurosci
JT  - Psychiatry and clinical neurosciences
JID - 9513551
RN  - 0 (Brain-Derived Neurotrophic Factor)
SB  - IM
MH  - Asian People/genetics
MH  - Brain-Derived Neurotrophic Factor/*genetics
MH  - Case-Control Studies
MH  - Genetic Association Studies
MH  - Genetic Predisposition to Disease/*genetics
MH  - Humans
MH  - Polymorphism, Single Nucleotide
MH  - Schizophrenia/*genetics
MH  - White People/genetics
EDAT- 2013/02/27 06:00
MHDA- 2014/01/31 06:00
CRDT- 2013/02/27 06:00
PHST- 2012/10/02 00:00 [received]
PHST- 2012/12/01 00:00 [revised]
PHST- 2012/12/12 00:00 [accepted]
PHST- 2013/02/27 06:00 [entrez]
PHST- 2013/02/27 06:00 [pubmed]
PHST- 2014/01/31 06:00 [medline]
AID - 10.1111/pcn.12018 [doi]
PST - ppublish
SO  - Psychiatry Clin Neurosci. 2013 Feb;67(2):123-5. doi: 10.1111/pcn.12018.