PMID- 23440163 OWN - NLM STAT- MEDLINE DCOM- 20130712 LR - 20140203 IS - 1539-3704 (Electronic) IS - 0003-4819 (Linking) VI - 158 IP - 9 DP - 2013 May 7 TI - Vitamin D and calcium supplementation to prevent fractures in adults: U.S. Preventive Services Task Force recommendation statement. PG - 691-6 LID - 10.7326/0003-4819-158-9-201305070-00603 [doi] AB - DESCRIPTION: New U.S. Preventive Services Task Force (USPSTF) recommendation statement on vitamin D and calcium supplementation to prevent fractures in adults. METHODS: The USPSTF commissioned 2 systematic evidence reviews and a meta-analysis on vitamin D supplementation with or without calcium to assess the effects of supplementation on bone health outcomes in community-dwelling adults, the association of vitamin D and calcium levels with bone health outcomes, and the adverse effects of supplementation. POPULATION: These recommendations apply to noninstitutionalized or community-dwelling asymptomatic adults without a history of fractures. This recommendation does not apply to the treatment of persons with osteoporosis or vitamin D deficiency. RECOMMENDATION: The USPSTF concludes that the current evidence is insufficient to assess the balance of the benefits and harms of combined vitamin D and calcium supplementation for the primary prevention of fractures in premenopausal women or in men. (I statement)The USPSTF concludes that the current evidence is insufficient to assess the balance of the benefits and harms of daily supplementation with greater than 400 IU of vitamin D3 and greater than 1000 mg of calcium for the primary prevention of fractures in noninstitutionalized postmenopausal women. (I statement)The USPSTF recommends against daily supplementation with 400 IU or less of vitamin D3 and 1000 mg or less of calcium for the primary prevention of fractures in noninstitutionalized postmenopausal women. (D recommendation). FAU - Moyer, Virginia A AU - Moyer VA AD - U.S. Preventive Services Task Force, Rockville, Maryland, USA. CN - U.S. Preventive Services Task Force* LA - eng PT - Journal Article PT - Practice Guideline PT - Research Support, U.S. Gov't, P.H.S. PL - United States TA - Ann Intern Med JT - Annals of internal medicine JID - 0372351 RN - 0 (Calcium, Dietary) RN - 1406-16-2 (Vitamin D) SB - IM CIN - Ann Intern Med. 2013 May 7;158(9):701-2. PMID: 23440174 SPIN- Ann Intern Med. 2013 May 7;158(9):I-36. PMID: 23440177 CIN - Ann Intern Med. 2013 Dec 17;159(12):856. PMID: 24343396 CIN - Ann Intern Med. 2013 Dec 17;159(12):856. PMID: 24343397 CIN - Ann Intern Med. 2013 Dec 17;159(12):856-7. PMID: 24490274 MH - Adult MH - Calcium, Dietary/*therapeutic use MH - *Dietary Supplements MH - Female MH - Fractures, Bone/*prevention & control MH - Humans MH - Male MH - Postmenopause MH - Premenopause MH - *Primary Prevention MH - Risk Assessment MH - Vitamin D/*therapeutic use FIR - Moyer, Virginia A IR - Moyer VA FIR - LeFevre, Michael L IR - LeFevre ML FIR - Siu, Albert L IR - Siu AL FIR - Baumann, Linda Ciofu IR - Baumann LC FIR - Bibbins-Domingo, Kirsten IR - Bibbins-Domingo K FIR - Curry, Susan J IR - Curry SJ FIR - Ebell, Mark IR - Ebell M FIR - Flores, Glenn IR - Flores G FIR - Cantu, Adelita Gonzales IR - Cantu AG FIR - Grossman, David C IR - Grossman DC FIR - Herzstein, Jessica IR - Herzstein J FIR - Nicholson, Wanda K IR - Nicholson WK FIR - Owens, Douglas K IR - Owens DK FIR - Petitti, Diana IR - Petitti D FIR - Wilt, Timothy J IR - Wilt TJ FIR - Melnyk, Bernadette IR - Melnyk B EDAT- 2013/02/27 06:00 MHDA- 2013/07/16 06:00 CRDT- 2013/02/27 06:00 PHST- 2013/02/27 06:00 [entrez] PHST- 2013/02/27 06:00 [pubmed] PHST- 2013/07/16 06:00 [medline] AID - 1655858 [pii] AID - 10.7326/0003-4819-158-9-201305070-00603 [doi] PST - ppublish SO - Ann Intern Med. 2013 May 7;158(9):691-6. doi: 10.7326/0003-4819-158-9-201305070-00603.