PMID- 23452467
OWN - NLM
STAT- MEDLINE
DCOM- 20130826
LR  - 20130318
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1284
DP  - 2013 Apr 5
TI  - An efficient method for the determination of furan derivatives in apple cider and 
      wine by solid phase extraction and high performance liquid chromatography--diode 
      array detector.
PG  - 100-6
LID - S0021-9673(13)00253-7 [pii]
LID - 10.1016/j.chroma.2013.02.002 [doi]
AB  - A reliable SPE-HPLC/DAD method was developed for the simultaneous separation and 
      quantitation of 10 furan derivatives in apple cider and wine matrices, including 
      5-hydroxymethyl-2-furaldehyde (5-HMFD), 4-hydroxy-2,5-dimethyl-3(2H)-furanone 
      (4-HDMF), 2-furoic acid (2-FA), 2-furaldehyde (2-F), 3-furaldehyde (3-F), 
      2-acetylfuran (2-AF), 5-methyl-2-furaldehyde (5-MFD), methyl 2-furoate (MFT), 
      2-propionylfuran (2-PF) and ethyl 2-furoate (EFT). All the compounds were 
      satisfactorily separated on a C18 column in less than 30 min. The solid phase 
      extraction parameters have been optimized, including the sorbent, sample volume, 
      washing and elution solvent. The relative standard deviations (RSDs) (intra- and 
      inter-day) of all analytes were less than 6.4% for apple cider at 5mg/L spiking 
      level and less than 3.9% (except 2-FA) for wine at 0.5mg/L spiking level. The 
      limits of detection (LOD) and limits of quantitation (LOQ) were low (LOD 
      0.002-0.093 mg/L, LOQ 0.01-0.31 mg/L) compared to the usual concentrations of 
      these compounds in these food matrices. The absolute recoveries of all compounds 
      were higher than 77.8% (most of them were 80.5-103%) at different spiking levels 
      (apple cider 0.5-50mg/L). The results showed that the developed method was 
      precise, sensitive, robust and of good selectivity.
CI  - Crown Copyright (c) 2013. Published by Elsevier B.V. All rights reserved.
FAU - Hu, Gaofei
AU  - Hu G
AD  - Guelph Food Research Centre, Agriculture and Agri-Food Canada, Guelph, ON, 
      Canada.
FAU - Hernandez, Marta
AU  - Hernandez M
FAU - Zhu, Honghui
AU  - Zhu H
FAU - Shao, Suqin
AU  - Shao S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130208
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Furans)
SB  - IM
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Furans/*analysis/chemistry/isolation & purification
MH  - Limit of Detection
MH  - Malus/*chemistry
MH  - Reproducibility of Results
MH  - Solid Phase Extraction/*methods
MH  - Wine/*analysis
EDAT- 2013/03/05 06:00
MHDA- 2013/08/27 06:00
CRDT- 2013/03/05 06:00
PHST- 2012/11/01 00:00 [received]
PHST- 2013/01/31 00:00 [revised]
PHST- 2013/02/01 00:00 [accepted]
PHST- 2013/03/05 06:00 [entrez]
PHST- 2013/03/05 06:00 [pubmed]
PHST- 2013/08/27 06:00 [medline]
AID - S0021-9673(13)00253-7 [pii]
AID - 10.1016/j.chroma.2013.02.002 [doi]
PST - ppublish
SO  - J Chromatogr A. 2013 Apr 5;1284:100-6. doi: 10.1016/j.chroma.2013.02.002. Epub 
      2013 Feb 8.