PMID- 23464319
OWN - NLM
STAT- MEDLINE
DCOM- 20130918
LR  - 20211021
IS  - 2473-4209 (Electronic)
IS  - 0094-2405 (Print)
IS  - 0094-2405 (Linking)
VI  - 40
IP  - 3
DP  - 2013 Mar
TI  - The feasibility of an inverse geometry CT system with stationary source arrays.
PG  - 031904
LID - 10.1118/1.4789918 [doi]
LID - 031904
AB  - PURPOSE: Inverse geometry computed tomography (IGCT) has been proposed as a new 
      system architecture that combines a small detector with a large, distributed 
      source. This geometry can suppress cone-beam artifacts, reduce scatter, and 
      increase dose efficiency. However, the temporal resolution of IGCT is still 
      limited by the gantry rotation time. Large reductions in rotation time are in 
      turn difficult due to the large source array and associated power electronics. We 
      examine the feasibility of using stationary source arrays for IGCT in order to 
      achieve better temporal resolution. We anticipate that multiple source arrays are 
      necessary, with each source array physically separated from adjacent ones. 
      METHODS: Key feasibility issues include spatial resolution, artifacts, flux, 
      noise, collimation, and system timing clashes. The separation between the 
      different source arrays leads to missing views, complicating reconstruction. For 
      the special case of three source arrays, a two-stage reconstruction algorithm is 
      used to estimate the missing views. Collimation is achieved using a rotating 
      collimator with a small number of holes. A set of equally spaced source spots are 
      designated on the source arrays, and a source spot is energized when a collimator 
      hole is aligned with it. System timing clashes occur when multiple source spots 
      are scheduled to be energized simultaneously. We examine flux considerations to 
      evaluate whether sufficient flux is available for clinical applications. RESULTS: 
      The two-stage reconstruction algorithm suppresses cone-beam artifacts while 
      maintaining resolution and noise characteristics comparable to standard third 
      generation systems. The residual artifacts are much smaller in magnitude than the 
      cone-beam artifacts eliminated. A mathematical condition is given relating 
      collimator hole locations and the number of virtual source spots for which system 
      timing clashes are avoided. With optimization, sufficient flux may be achieved 
      for many clinical applications. CONCLUSIONS: IGCT with stationary source arrays 
      could be an imaging platform potentially capable of imaging a complete 16-cm 
      thick volume within a tenth of a second.
FAU - Hsieh, Scott S
AU  - Hsieh SS
AD  - Department of Radiology, Stanford University, Stanford, California 94305, USA.
FAU - Heanue, Joseph A
AU  - Heanue JA
FAU - Funk, Tobias
AU  - Funk T
FAU - Hinshaw, Waldo S
AU  - Hinshaw WS
FAU - Wilfley, Brian P
AU  - Wilfley BP
FAU - Solomon, Edward G
AU  - Solomon EG
FAU - Pelc, Norbert J
AU  - Pelc NJ
LA  - eng
GR  - R01 EB006837/EB/NIBIB NIH HHS/United States
GR  - R01EB006837/EB/NIBIB NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PL  - United States
TA  - Med Phys
JT  - Medical physics
JID - 0425746
SB  - IM
MH  - Equipment Design
MH  - Feasibility Studies
MH  - Image Processing, Computer-Assisted
MH  - Tomography, X-Ray Computed/instrumentation/*methods
PMC - PMC3585759
EDAT- 2013/03/08 06:00
MHDA- 2013/09/21 06:00
PMCR- 2014/03/01
CRDT- 2013/03/08 06:00
PHST- 2013/03/08 06:00 [entrez]
PHST- 2013/03/08 06:00 [pubmed]
PHST- 2013/09/21 06:00 [medline]
PHST- 2014/03/01 00:00 [pmc-release]
AID - 019303MPH [pii]
AID - 10.1118/1.4789918 [doi]
PST - ppublish
SO  - Med Phys. 2013 Mar;40(3):031904. doi: 10.1118/1.4789918.