PMID- 23468169 OWN - NLM STAT- MEDLINE DCOM- 20140623 LR - 20211021 IS - 1573-2649 (Electronic) IS - 0962-9343 (Linking) VI - 22 IP - 9 DP - 2013 Nov TI - Comparative responsiveness and minimal change of the Knee Quality of Life 26-item (KQoL-26) questionnaire. PG - 2461-75 LID - 10.1007/s11136-012-0298-0 [doi] AB - OBJECTIVES: To assess the responsiveness of the KQoL-26 and demonstrate minimal change for this instrument in two different samples of patients with suspected internal derangement of the knee. METHODS: Data were collected from two surveys conducted alongside a clinical trial: the arthroscopy sample and the general practitioner (GP) sample. The effect size (ES) was used to assess responsiveness. Anchor-based minimal change included minimal clinical important difference (MCID) and receiver operator characteristic curves; standardized error of measurement and minimal detectable change (MDC) was employed for distribution-based approaches. The KQoL-26 results are compared with those for the Lysholm Knee Score, EQ-5D and SF-36. RESULTS: The arthroscopy sample consisted of 121 participants and the GP sample of 218 participants at baseline. The largest ES was found for the KQoL-26 emotional functioning scale in both samples. The results were in favour of the condition-specific instrument. The MCID for KQoL-26 physical functioning, activities limitations and emotional functioning scales were 3, 15 and 18, respectively, in the arthroscopy sample; they were 11, 16 and 24 in the GP sample. The MDC 95 % was estimated as 18, 28 and 34, and 15, 24 and 30 in each sample, respectively. CONCLUSIONS: The KQoL-26 emotional functional scale was the most responsive of all scales. It is recommended that an instrument such as the KQoL-26 that includes emotional functioning should be included rather than the Lysholm in future clinical trials of patients with suspected internal derangement of the knee. FAU - Chuang, Ling-Hsiang AU - Chuang LH AD - York Trials Unit, Department of Health Sciences, York, UK. FAU - Garratt, Andrew AU - Garratt A FAU - Brealey, Stephen AU - Brealey S LA - eng GR - G0001133/MRC_/Medical Research Council/United Kingdom PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20130307 PL - Netherlands TA - Qual Life Res JT - Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation JID - 9210257 SB - IM MH - Arthroscopy MH - Data Collection MH - Disability Evaluation MH - *Emotions MH - Female MH - Follow-Up Studies MH - General Practitioners/statistics & numerical data MH - Humans MH - Knee Injuries/*physiopathology/surgery MH - Male MH - Middle Aged MH - Psychometrics/*instrumentation MH - *Quality of Life MH - Surveys and Questionnaires EDAT- 2013/03/08 06:00 MHDA- 2014/06/24 06:00 CRDT- 2013/03/08 06:00 PHST- 2012/10/16 00:00 [accepted] PHST- 2013/03/08 06:00 [entrez] PHST- 2013/03/08 06:00 [pubmed] PHST- 2014/06/24 06:00 [medline] AID - 10.1007/s11136-012-0298-0 [doi] PST - ppublish SO - Qual Life Res. 2013 Nov;22(9):2461-75. doi: 10.1007/s11136-012-0298-0. Epub 2013 Mar 7.