PMID- 23470270
OWN - NLM
STAT- MEDLINE
DCOM- 20140324
LR  - 20161125
IS  - 1538-2990 (Electronic)
IS  - 0002-9629 (Linking)
VI  - 347
IP  - 2
DP  - 2014 Feb
TI  - Cardiac magnetic resonance imaging in peripartum cardiomyopathy.
PG  - 112-7
LID - 10.1097/MAJ.0b013e31828155e3 [doi]
AB  - BACKGROUND: Peripartum cardiomyopathy (PPCM) is a rare life-threatening condition 
      of unclear etiology. Data on the use of cardiac magnetic resonance (CMR) imaging 
      to characterize PPCM are limited. This study was done to assess the role of CMR 
      imaging for the diagnosis and prognostication of patients with PPCM. METHODS: 
      Medical records of a tertiary medical center were screened for PPCM patients with 
      CMR imaging done within the past 5 years (2006-2011). Images were reviewed by 2 
      expert radiologists (blinded to clinical data) using cine sequences for chamber 
      function and size, T2-weighted images for the determination of edema (T2-ratio), 
      and late gadolinium enhancement (LGE) sequences for myocardial tissue 
      characterization. RESULTS: Ten PPCM patients (aged 28 +/- 6 years, 90% African 
      American) had a total of 15 CMR examinations: 4 in the acute phase (within 7 days 
      of diagnosis) and 11 during follow-up (median, 12 months; range, 1-72 months). 
      Left ventricular ejection fraction was decreased in all 4 initial scans. Elevated 
      T2 ratio (>2) seen in 1 patient decreased on follow-up imaging. LGE was seen in 1 
      of the 4 acute-phase scans and in 4 of the 11 follow-up phase scans. These 4 
      patients had multiple readmissions because of heart failure exacerbations and 
      persistently low left ventricular ejection fraction on subsequent 
      echocardiograms. CONCLUSIONS: LGE seems to be associated with a poor prognosis in 
      the setting of PPCM. CMR imaging seems to have promising practical implications 
      in the diagnosis and prognostication of PPCM patients.
FAU - Arora, Natasha Purai
AU  - Arora NP
AD  - Division of Cardiology, Department of Internal Medicine (NPA, NM, TM, AK, LCA), 
      Wayne State University School of Medicine, Detroit Medical Center, Detroit, 
      Michigan; and Department of Radiology (RD, TL), Wayne State University School of 
      Medicine, Detroit Medical Center, Detroit, Michigan.
FAU - Mohamad, Tamam
AU  - Mohamad T
FAU - Mahajan, Nitin
AU  - Mahajan N
FAU - Danrad, Raman
AU  - Danrad R
FAU - Kottam, Anupama
AU  - Kottam A
FAU - Li, Tao
AU  - Li T
FAU - Afonso, Luis C
AU  - Afonso LC
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Am J Med Sci
JT  - The American journal of the medical sciences
JID - 0370506
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Cardiomyopathies/*diagnosis/diagnostic imaging
MH  - Female
MH  - Humans
MH  - *Magnetic Resonance Imaging
MH  - *Peripartum Period
MH  - Pregnancy
MH  - Radiography
MH  - Retrospective Studies
MH  - Young Adult
EDAT- 2013/03/09 06:00
MHDA- 2014/03/25 06:00
CRDT- 2013/03/09 06:00
PHST- 2013/03/09 06:00 [entrez]
PHST- 2013/03/09 06:00 [pubmed]
PHST- 2014/03/25 06:00 [medline]
AID - S0002-9629(15)30408-0 [pii]
AID - 10.1097/MAJ.0b013e31828155e3 [doi]
PST - ppublish
SO  - Am J Med Sci. 2014 Feb;347(2):112-7. doi: 10.1097/MAJ.0b013e31828155e3.