PMID- 23473721
OWN - NLM
STAT- MEDLINE
DCOM- 20131104
LR  - 20151119
IS  - 1878-4046 (Electronic)
IS  - 1076-6332 (Linking)
VI  - 20
IP  - 6
DP  - 2013 Jun
TI  - Comparison of 3D phase-sensitive inversion-recovery and 2D inversion-recovery MRI 
      at 3.0 T for the assessment of late gadolinium enhancement in patients with 
      hypertrophic cardiomyopathy.
PG  - 752-7
LID - S1076-6332(13)00036-6 [pii]
LID - 10.1016/j.acra.2013.01.014 [doi]
AB  - RATIONALE AND OBJECTIVES: To compare free-breathing three-dimensional (3D) 
      phase-sensitive inversion recovery (PSIR) with breath-holding two-dimensional 
      (2D) IR sequences to determine which is better for detecting and characterizing 
      myocardial late gadolinium enhancement (LGE) in hypertrophic cardiomyopathy (HCM) 
      patients. MATERIALS AND METHODS: Thirty HCM patients clinically underwent 3.0 T 
      cardiac magnetic resonance imaging that included 3D-PSIR and 2D-IR. The amount of 
      LGE lesions was calculated and expressed as %LGE of the myocardial mass, and the 
      average of the %LGE value reported by two observers was recorded as the final 
      %LGE. We also counted the number of LGE lesions and recorded their location. The 
      myocardium-LGE contrast, margin sharpness, artifacts, and overall image quality 
      were graded on a 4-point grading scale (1 = poor, 2 = fair, 3 = good, 
      4 = excellent). RESULTS: The mean %LGE on 2D-IR was 24.7 +/- 0.6, 17.5 +/- 0.6, and 
      8.5 +/- 0.3, respectively, for the basal, mid-, and apical myocardium; the 
      corresponding values were 24.2 +/- 0.4, 20.0 +/- 0.4, and 7.7 +/- 0.3 on 3D-PSIR (2D-IR 
      versus 3D-PSIR, P = .87). On 2D IR and 3D-PSIR images, 13, 52, and 53, and 9, 74, 
      and 33 LGE lesions were detected in the subendocardial, midwall, subepicardial 
      area, respectively. The myocardium-LGE contrast and overall image quality were 
      significantly higher on 3D-PSIR than 2D-IR images (P < .001); the sequences did 
      not differ significantly with respect to margin sharpness and artifact. 
      CONCLUSION: Three-dimensional PSIR sequence yields higher image contrast, better 
      image quality, and greater detection ability for LGE lesions than 2D-IR sequence.
CI  - Copyright (c) 2013 AUR. Published by Elsevier Inc. All rights reserved.
FAU - Morita, Kosuke
AU  - Morita K
AD  - Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, Kumamoto, 
      Japan.
FAU - Utsunomiya, Daisuke
AU  - Utsunomiya D
FAU - Oda, Seitaro
AU  - Oda S
FAU - Komi, Masanori
AU  - Komi M
FAU - Namimoto, Tomohiro
AU  - Namimoto T
FAU - Hirai, Toshinori
AU  - Hirai T
FAU - Hashida, Masahiro
AU  - Hashida M
FAU - Takashio, Seiji
AU  - Takashio S
FAU - Yamamuro, Megumi
AU  - Yamamuro M
FAU - Yamashita, Yasuyuki
AU  - Yamashita Y
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20130306
PL  - United States
TA  - Acad Radiol
JT  - Academic radiology
JID - 9440159
RN  - 0 (Contrast Media)
RN  - K2I13DR72L (Gadolinium DTPA)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - *Algorithms
MH  - Cardiomyopathy, Hypertrophic/*pathology
MH  - Contrast Media/administration & dosage
MH  - Female
MH  - Gadolinium DTPA/*administration & dosage
MH  - Humans
MH  - Image Enhancement/methods
MH  - Image Interpretation, Computer-Assisted/*methods
MH  - Imaging, Three-Dimensional/*methods
MH  - Magnetic Resonance Imaging/*methods
MH  - Male
MH  - Middle Aged
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
EDAT- 2013/03/12 06:00
MHDA- 2013/11/05 06:00
CRDT- 2013/03/12 06:00
PHST- 2012/10/29 00:00 [received]
PHST- 2013/01/26 00:00 [revised]
PHST- 2013/01/26 00:00 [accepted]
PHST- 2013/03/12 06:00 [entrez]
PHST- 2013/03/12 06:00 [pubmed]
PHST- 2013/11/05 06:00 [medline]
AID - S1076-6332(13)00036-6 [pii]
AID - 10.1016/j.acra.2013.01.014 [doi]
PST - ppublish
SO  - Acad Radiol. 2013 Jun;20(6):752-7. doi: 10.1016/j.acra.2013.01.014. Epub 2013 Mar 
      6.