PMID- 23474361
OWN - NLM
STAT- MEDLINE
DCOM- 20131022
LR  - 20130410
IS  - 1557-3117 (Electronic)
IS  - 1053-2498 (Linking)
VI  - 32
IP  - 5
DP  - 2013 May
TI  - Left ventricular device implantation for advanced cardiac amyloidosis.
PG  - 563-8
LID - S1053-2498(13)01024-3 [pii]
LID - 10.1016/j.healun.2013.01.987 [doi]
AB  - The purpose of this study was to analyze the post-hospital outcomes in patients 
      with senile or familial cardiac amyloidosis treated with left ventricular assist 
      device (LVAD) implantation. From December 1, 2008 to May 31, 2012, a total of 9 
      patients underwent LVAD placement for heart failure secondary to amyloidosis. 
      Prior to LVAD placement, all patients were New York Heart Association (NYHA) 
      Class IV and had a significantly decreased cardiac index (mean 1.93 
      liters/min/m(2) [1.64 to 2.36]). All patients tolerated LVAD implantation well. 
      Post-operatively, 2 patients died prior to hospital discharge. Three patients 
      died since discharge with a median survival of 13.7 months. Four patients 
      remained alive with a follow-up of 16-24 months. The most common adverse event 
      since placement has been gastrointestinal bleeding (3 of 9 patients). Firm 
      conclusions cannot be drawn from our investigation, but the present observations 
      suggest LVAD implantation is technically feasible for patients with severe heart 
      failure due to advanced cardiac amyloidosis.
CI  - Copyright (c) 2013 International Society for Heart and Lung Transplantation. 
      Published by Elsevier Inc. All rights reserved.
FAU - Swiecicki, Paul L
AU  - Swiecicki PL
AD  - Division of Hematology, Mayo Clinic, Rochester, Minnesota 55902, USA.
FAU - Edwards, Brooks S
AU  - Edwards BS
FAU - Kushwaha, Sudhir S
AU  - Kushwaha SS
FAU - Dispenzieri, Angela
AU  - Dispenzieri A
FAU - Park, Soon J
AU  - Park SJ
FAU - Gertz, Morie A
AU  - Gertz MA
LA  - eng
PT  - Journal Article
DEP - 20130306
PL  - United States
TA  - J Heart Lung Transplant
JT  - The Journal of heart and lung transplantation : the official publication of the 
      International Society for Heart Transplantation
JID - 9102703
SB  - IM
MH  - Aged
MH  - Amyloidosis/diagnosis/mortality/*therapy
MH  - Follow-Up Studies
MH  - Heart Diseases/diagnosis/mortality/*therapy
MH  - *Heart-Assist Devices
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prognosis
MH  - Retrospective Studies
MH  - Survival Rate
MH  - Treatment Outcome
EDAT- 2013/03/12 06:00
MHDA- 2013/10/23 06:00
CRDT- 2013/03/12 06:00
PHST- 2012/07/21 00:00 [received]
PHST- 2013/01/10 00:00 [revised]
PHST- 2013/01/14 00:00 [accepted]
PHST- 2013/03/12 06:00 [entrez]
PHST- 2013/03/12 06:00 [pubmed]
PHST- 2013/10/23 06:00 [medline]
AID - S1053-2498(13)01024-3 [pii]
AID - 10.1016/j.healun.2013.01.987 [doi]
PST - ppublish
SO  - J Heart Lung Transplant. 2013 May;32(5):563-8. doi: 10.1016/j.healun.2013.01.987. 
      Epub 2013 Mar 6.