PMID- 23480769 OWN - NLM STAT- MEDLINE DCOM- 20160422 LR - 20181202 IS - 2476-762X (Electronic) IS - 1513-7368 (Linking) VI - 13 Suppl DP - 2012 TI - Viral hepatitis B, C infection and genotype distribution among cholangiocarcinoma patients in northeast Thailand. PG - 83-7 AB - The prevalence of HBV and HCV infection among 295 cholangiocarcinoma (CCA) patients in northeast Thailand was analyzed. Hepatitis B surface antigen (HBsAg) was detected in 8.8% (26/295 cases) and antibodies to HCV (anti-HCV) in 2.7% (8/295 cases) of CCA cases. Screening for HBV DNA was performed in 15 of 26 HBV seropositive cases and genotypes could be determined in all 15. HBV genotypes C and B were detected in 73.3% (11/15 cases) and 26.7% (4/15 cases), respectively. HCV RNA was detected in 87.5% (7/8 cases) of anti-HCV positive cases. Specifically, 57.1% (4/7 cases) were HCV genotype 1a and 42.9% (3/7 cases) were HCV genotype 3a. The prevalence of infection and genotype distribution of both HCV and HBV among CCA in northeast Thailand is comparable to that in the general population, suggesting that HCV and HBV infections are, if at all, not serious risk factors for CCA. FAU - Barusrux, Sahapat AU - Barusrux S AD - Department of Clinical Immunology and Transfusion Medicine, Centre for Research and Development of Medical Diagnostic Laboratories, Khon Kaen University, Khon Kaen, Thailand. sahapat@kku.ac.th FAU - Nanok, Chaiyachet AU - Nanok C FAU - Puthisawas, Watcharapong AU - Puthisawas W FAU - Pairojkul, Chawalit AU - Pairojkul C FAU - Poovorawan, Yong AU - Poovorawan Y LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Thailand TA - Asian Pac J Cancer Prev JT - Asian Pacific journal of cancer prevention : APJCP JID - 101130625 SB - IM MH - Bile Duct Neoplasms MH - Bile Ducts, Intrahepatic MH - Cholangiocarcinoma MH - Genotype MH - *Hepatitis B/epidemiology MH - Hepatitis B virus/genetics MH - *Hepatitis C/epidemiology MH - Humans MH - Thailand EDAT- 2012/01/01 00:00 MHDA- 2016/04/23 06:00 CRDT- 2013/03/14 06:00 PHST- 2013/03/14 06:00 [entrez] PHST- 2012/01/01 00:00 [pubmed] PHST- 2016/04/23 06:00 [medline] AID - 27150 [pii] PST - ppublish SO - Asian Pac J Cancer Prev. 2012;13 Suppl:83-7.